Shaimaa Hamarsheh
Overview
Explore the profile of Shaimaa Hamarsheh including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
431
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Recent Articles
1.
Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Buttner-Herold M, Bach C, et al.
Immunity
. 2021 Jul;
54(8):1772-1787.e9.
PMID: 34289378
As substantial constituents of the multiple myeloma (MM) microenvironment, pro-inflammatory macrophages have emerged as key promoters of disease progression, bone destruction, and immune impairment. We identify beta-2-microglobulin (β2m) as a...
2.
Osswald L, Hamarsheh S, Uhl F, Andrieux G, Klein C, Dierks C, et al.
Mol Cancer Res
. 2021 Jun;
19(9):1596-1608.
PMID: 34088868
The bone marrow microenvironment (BMME) is key player in regulation and maintenance of hematopoiesis. Oncogenic mutations, causing constitutive activation of multiple tumor-promoting pathways, are frequently found in human cancer. So...
3.
Hamarsheh S, Gross O, Brummer T, Zeiser R
Nat Commun
. 2020 Oct;
11(1):5439.
PMID: 33116132
Oncogenic KRAS mutations are the most frequent mutations in human cancer, but most difficult to target. While sustained proliferation caused by oncogenic KRAS-downstream signalling is a main driver of carcinogenesis,...
4.
Hamarsheh S, Zeiser R
Front Immunol
. 2020 Aug;
11:1444.
PMID: 32733479
Inflammation is involved in tumor development and progression as well as antitumor response to therapy. In the past decade, the crosstalk between inflammation, immunity, and cancer has been investigated extensively,...
5.
Hamarsheh S, Osswald L, Saller B, Unger S, De Feo D, Vinnakota J, et al.
Nat Commun
. 2020 Apr;
11(1):1659.
PMID: 32246016
Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here,...
6.
Mathew N, Vinnakota J, Apostolova P, Erny D, Hamarsheh S, Andrieux G, et al.
J Clin Invest
. 2019 Dec;
130(3):1315-1329.
PMID: 31846439
Acute graft-versus-host disease (GVHD) can affect the central nervous system (CNS). The role of microglia in CNS-GVHD remains undefined. In agreement with microglia activation, we found that profound morphological changes...