Shahram Y Kordasti
Overview
Explore the profile of Shahram Y Kordasti including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
354
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0
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Recent Articles
1.
Afzali B, Mitchell P, Edozie F, Povoleri G, Dowson S, Demandt L, et al.
Eur J Immunol
. 2013 May;
43(8):2043-54.
PMID: 23677517
Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are "plastic", and are able to produce...
2.
Afzali B, Edozie F, Fazekasova H, Scotta C, Mitchell P, Canavan J, et al.
Clin J Am Soc Nephrol
. 2013 Apr;
8(8):1396-405.
PMID: 23580782
Background And Objectives: Cell-based therapy with natural (CD4(+)CD25(hi)CD127(lo)) regulatory T cells to induce transplant tolerance is now technically feasible. However, regulatory T cells from hemodialysis patients awaiting transplantation may be...
3.
Costantini B, Kordasti S, Kulasekararaj A, Jiang J, Seidl T, Perez Abellan P, et al.
Haematologica
. 2012 Dec;
98(8):1196-205.
PMID: 23242597
Expansion of regulatory T cells occurs in high-risk myelodysplastic syndrome and correlates with a poor prognosis. DNA methyltransferase inhibitors, particularly 5-azacytidine, have been shown to increase the survival of patients...
4.
Kordasti S, Afzali B, Lim Z, Ingram W, Hayden J, Barber L, et al.
Br J Haematol
. 2009 Feb;
145(1):64-72.
PMID: 19210506
Immunological responses are increasingly recognised as being important in the initiation and progression of myelodysplastic syndrome (MDS). Indeed, autoimmune diseases commonly occur in association with MDS, particularly in subtypes with...
5.
Kordasti S, Ingram W, Hayden J, Darling D, Barber L, Afzali B, et al.
Blood
. 2007 Apr;
110(3):847-50.
PMID: 17412885
Foxp3+ regulatory T cells (Tregs) play a central role in maintaining immune tolerance. A reduction in the function of Tregs is a key feature of autoimmune diseases, whereas their expansion...