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Shahina Daar

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Articles 114
Citations 1183
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Recent Articles
1.
De Sanctis V, Canatan D, Daar S, Kattamis C, Banchev A, Modeva I, et al.
Mediterr J Hematol Infect Dis . 2025 Jan; 17(1):e2025008. PMID: 39830799
Background: Current guidelines for screening glucose dysregulation (GD) in patients with transfusion-dependent thalassemia (TDT) recommend an annual 2-hour oral glucose tolerance test (OGTT) starting at the age of 10 years....
2.
Al-Naamani K, Omar H, Al Busafi S, Al Shuaili H, Al-Naamani Z, Al-Khabori M, et al.
J Clin Med . 2024 Dec; 13(23). PMID: 39685869
: The advent of direct-acting antiviral (DAA) therapy has revolutionized the treatment landscape of the hepatitis C virus (HCV) infection. This study aimed to provide a comprehensive research study of...
3.
De Sanctis V, Soliman A, Daar S, Tzoulis P, Kattamis C
Mediterr J Hematol Infect Dis . 2024 Jan; 16(1):e2024005. PMID: 38223478
Background: Prediabetes and diabetes mellitus (DM) are complications in adult patients with transfusion-dependent β-thalassemia (β-TDT), with their incidence increasing with age. Objective: This retrospective observational study describes the glycemic trajectories...
4.
De Sanctis V, Daar S, Soliman A, Tzoulis P, Yassin M, Kattamis C
Acta Biomed . 2023 Dec; 94(6):e2023262. PMID: 38054678
Aims: Non-transfusion - dependent β-thalassemias (NTD-βThal) can cause iron overload and serious iron-related organ complications as endocrine dysfunction, including glucose dysregulation (GD). Patients And Methods: We retrieved data of all...
5.
De Sanctis V, Soliman A, Daar S, Tzoulis P, Karimi M, Saki F, et al.
Acta Biomed . 2023 Dec; 94(6):e2023221. PMID: 38054665
The gold standard for the measurement of insulin secretion is the hyperglycemic clamp and for insulin sensitivity the hyperinsulinemic euglycemic clamp, respectively. A number of surrogate indices, derived from plasma...
6.
Di Maio S, Marzuillo P, Daar S, Kattamis C, Karimi M, Forough S, et al.
Mediterr J Hematol Infect Dis . 2023 Nov; 15(1):e2023058. PMID: 38028391
Introduction: To evaluate the effect of early chelation therapy (≤ 3 years) with a variety of chelating agents on age at menarche and menstrual characteristics in patients with transfusion-dependent thalassemia...
7.
De Sanctis V, Daar S, Soliman A, Tzoulis P, Yassin M, Kattamis C
Acta Biomed . 2023 Oct; 94(5):e2023225. PMID: 37850764
Background: With the rising prevalence of obesity worldwide, it is becoming imperative to detect disturbed glucose metabolism as early as possible in order to prevent type 2 diabetes (T2D) development....
8.
De Sanctis V, Daar S, Soliman A, Tzoulis P, Di Maio S, Kattamis C
Acta Biomed . 2023 Aug; 94(4):e2023195. PMID: 37539597
Background And Aim: Hypogonadism and abnormalities of glucose homeostasis, resulting from iron-induced pituitary and pancreatic β-cell dysfunction respectively, are the most frequently reported endocrine abnormalities in patients with ß-thalassemia major...
9.
Daar S, Al-Naamani K, De Sanctis V, Al Rahbi S, Al Zadjali S, Khan H, et al.
Acta Biomed . 2023 Aug; 94(4):e2023191. PMID: 37539594
Beta thalassemia major (β-TM) is a genetic blood disorder requiring lifelong blood transfusions.  The resulting iron overload damages multiple organs, particularly the heart and endocrine organs. This study aimed to...
10.
De Sanctis V, Daar S, Soliman A, Tzoulis P, Di Maio S, Kattamis C
Acta Biomed . 2023 Jun; 94(3):e2023065. PMID: 37326269
Background: Acquired ypogonadotropic hypogonadism (AHH) is the most prevalent endocrine complication in thalassemia major (TM). Study Design: Considering the detrimental effect of estrogen deficiency on glucose metabolism, the ICET-A Network...