Shahar Azar
Overview
Explore the profile of Shahar Azar including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
159
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0
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Recent Articles
1.
Higazi A, Maraga E, Baraghithy S, Udi S, Azar S, Saada A, et al.
iScience
. 2024 Feb;
27(2):108802.
PMID: 38318380
Inflammation is consistently linked to dysmetabolism. In transgenic mice (Def) model the neutrophilic peptide, alpha defensin, proved atherogenic. This phenotype occurred despite favorable cholesterol and glucose levels, and lower body...
2.
Hirsch S, Hinden L, Naim M, Baraghithy S, Permyakova A, Azar S, et al.
J Control Release
. 2022 Nov;
353:254-269.
PMID: 36442615
Over-activation of the endocannabinoid/CBR system is a hallmark feature of obesity and its related comorbidities, most notably type 2 diabetes (T2D), and non-alcoholic fatty liver disease (NAFLD). Although the use...
3.
Abuhasira R, Azar S, Nemirovski A, Tam J, Novack V
Life (Basel)
. 2022 Oct;
12(10).
PMID: 36294974
Activation of the endocannabinoid system has various cardiovascular and metabolic expressions, including increased lipogenesis, decreased blood pressure, increased heart rate, and changes in cholesterol levels. There is a scarcity of...
4.
Ben-Cnaan E, Permyakova A, Azar S, Hirsch S, Baraghithy S, Hinden L, et al.
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628417
Obesity is a global medical problem; its common form is known as diet-induced obesity (DIO); however, there are several rare genetic disorders, such as Prader-Willi syndrome (PWS), that are also...
5.
Matalon S, Azar S, Meiri D, Hadar R, Nemirovski A, Abu Jabal N, et al.
Front Endocrinol (Lausanne)
. 2021 Sep;
12:685289.
PMID: 34531823
Background: Inflammatory bowel diseases (IBDs) are chronic, idiopathic, inflammatory, gastrointestinal disorders. The endocannabinoid system may have a role in the pathogenesis of IBD. We aimed to assess whether cannabis treatment...
6.
Ben-Haroush Schyr R, Al-Kurd A, Moalem B, Permyakova A, Israeli H, Bardugo A, et al.
Diabetes
. 2021 Aug;
70(10):2289-2298.
PMID: 34341005
Bariatric operations induce weight loss, which is associated with an improvement in hepatic steatosis and a reduction in hepatic glucose production. It is not clear whether these outcomes are entirely...
7.
Drori A, Gammal A, Azar S, Hinden L, Hadar R, Wesley D, et al.
Elife
. 2020 Nov;
9.
PMID: 33210603
The soluble isoform of leptin receptor (sOb-R), secreted by the liver, regulates leptin bioavailability and bioactivity. Its reduced levels in diet-induced obesity (DIO) contribute to hyperleptinemia and leptin resistance, effects...
8.
Azar S, Udi S, Drori A, Hadar R, Nemirovski A, Vemuri K, et al.
Mol Metab
. 2020 Sep;
42:101087.
PMID: 32987186
Objective: The endocannabinoid (eCB) system is increasingly recognized as being crucially important in obesity-related hepatic steatosis. By activating the hepatic cannabinoid-1 receptor (CBR), eCBs modulate lipogenesis and fatty acid oxidation....
9.
Azar S, Sherf-Dagan S, Nemirovski A, Webb M, Raziel A, Keidar A, et al.
Obes Surg
. 2018 Sep;
29(1):268-276.
PMID: 30244333
Background: The endocannabinoid (eCB) system plays a key role in the development of obesity and its comorbidities. Limited information exists on the changes in circulating eCBs following bariatric surgery. Objectives:...
10.
Tam J, Hinden L, Drori A, Udi S, Azar S, Baraghithy S
Eur J Intern Med
. 2018 Jan;
49:23-29.
PMID: 29336868
Endocannabinoids (eCBs) are internal lipid mediators recognized by the cannabinoid-1 and -2 receptors (CBR and CBR, respectively), which also mediate the different physiological effects of marijuana. The endocannabinoid system, consisting...