Sezer Akgol
Overview
Explore the profile of Sezer Akgol including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
15
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Recent Articles
1.
Anjum A, Mader M, Mahameed S, Muraly A, Denorme F, Kliem F, et al.
Blood
. 2025 Jan;
PMID: 39841014
Platelets are crucial players in hemostasis and thrombosis, but also contribute to immune regulation and host defense, using different receptors, signaling pathways and effector functions, respectively. Whether distinct subsets of...
2.
Kaiser R, Dewender R, Mulkers M, Stermann J, Rossaro D, Di Fina L, et al.
Blood
. 2024 Oct;
144(24):2546-2553.
PMID: 39440970
Platelets are key players in cardiovascular disease, and platelet aggregation represents a central pharmacologic target, particularly in secondary prevention. However, inhibition of adenosine diphosphate and thromboxane signaling has low efficacy...
3.
Pekayvaz K, Losert C, Knottenberg V, Gold C, van Blokland I, Oelen R, et al.
Nat Med
. 2024 May;
30(6):1696-1710.
PMID: 38773340
Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality. Inflammation is considered a key pathogenic driver of these diseases, but the underlying immune states and their...
4.
Kaiser R, Gold C, Joppich M, Loew Q, Akhalkatsi A, Mueller T, et al.
Sci Adv
. 2024 Mar;
10(12):eadl1710.
PMID: 38517968
Neutrophils rapidly respond to inflammation and infection, but to which degree their functional trajectories after mobilization from the bone marrow are shaped within the circulation remains vague. Experimental limitations have...
5.
Albayrak E, Akgol S, Turan R, Uslu M, Kocabas F
J Cell Biochem
. 2022 Sep;
123(12):2009-2029.
PMID: 36070493
Hematopoietic stem cells (HSCs), which are multipotent and have the ability to self-renew, are frequently used in the treatment of hematological diseases and cancer. Small molecules that target HSC quiescence...
6.
Siyah P, Akgol S, Durdagi S, Kocabas F
Biochem J
. 2021 Sep;
478(18):3445-3466.
PMID: 34486667
OTU proteases antagonize the cellular defense in the host cells and involve in pathogenesis. Intriguingly, P. falciparum, P. vivax, and P. yoelii have an uncharacterized and highly conserved viral OTU-like...
7.
SC1 limits tube formation, branching, migration, expansion and induce apoptosis of endothelial cells
Akgol S, Kalkan B, Yucel D, Kocabas F
Vascul Pharmacol
. 2021 Sep;
141:106903.
PMID: 34481979
Endothelial cells (ECs) are essential in the growth and progression of the tumor cells by supplying nutrition and angiogenesis factors. Targeting ECs emerged as a major strategy to prevent the...
8.
Albayrak E, Uslu M, Akgol S, Tuysuz E, Kocabas F
J Cell Physiol
. 2021 Jun;
236(12):8122-8136.
PMID: 34101829
Hematopoietic stem cells (HSCs) are particularly characterized by their quiescence and self-renewal. Cell cycle regulators tightly control quiescence and self-renewal capacity. Studies suggest that modulation of ubiquitination and neddylation could...
9.
Kalkan B, Akgol S, Ak D, Yucel D, Guney Esken G, Kocabas F
Microvasc Res
. 2020 Mar;
130:104001.
PMID: 32198058
Endothelial dysfunction is prominent in atherosclerosis, hypertension, diabetes, peripheral and cardiovascular diseases, and stroke. Novel therapeutic approaches to these conditions often involve development of tissue-engineered veins with ex vivo expanded...