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Seth A Bennett

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Articles 8
Citations 122
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Recent Articles
1.
Bennett S, Cobos S, Fisher R, Son E, Frederic R, Segal R, et al.
J Fungi (Basel) . 2025 Jan; 11(1). PMID: 39852477
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are incurable neurodegenerative disorders sharing pathological and genetic features, including mutations in the gene. FUS is an RNA-binding protein that mislocalizes to...
2.
Bennett S, Cobos S, Son E, Segal R, Mathew S, Yousuf H, et al.
MicroPubl Biol . 2023 Sep; 2023. PMID: 37746061
Mutations in the RNA-binding protein FUS are linked to amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD). FUS mutants mislocalize and aggregate in dying neurons. We previously established that FUS proteinopathy...
3.
Cobos S, Janani C, Cruz G, Rana N, Son E, Frederic R, et al.
Pathogens . 2022 Dec; 11(12). PMID: 36558770
Prions are proteins able to take on alternative conformations and propagate them in a self-templating process. In , prions enable heritable responses to environmental conditions through bet-hedging mechanisms. Hence, [PRION]...
4.
Bennett S, Cobos S, Mirzakandova M, Fallah M, Son E, Angelakakis G, et al.
Biochemistry . 2021 Nov; 60(48):3671-3675. PMID: 34788013
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease that often occurs concurrently with frontotemporal dementia (FTD), another disorder involving progressive neuronal loss. ALS and FTD form a neurodegenerative continuum...
5.
Hugais M, Cobos S, Bennett S, Paredes J, Foran G, Torrente M
MicroPubl Biol . 2021 Nov; 2021. PMID: 34746682
Alzheimer's Disease (AD), the most common type of dementia, is a neurodegenerative disease characterized by plaques of amyloid-beta (Aβ) peptides found in the cerebral cortex of the brain. The pathological...
6.
Bennett S, Cobos S, Meykler M, Fallah M, Rana N, Chen K, et al.
J Vis Exp . 2019 Apr; (145). PMID: 30958470
Neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD), cause the loss of hundreds of thousands of lives each year. Effective treatment options able to halt disease...
7.
Bennett S, Tanaz R, Cobos S, Torrente M
Transl Res . 2018 Nov; 204:19-30. PMID: 30391475
Amyotrophic lateral sclerosis (ALS) is the third most common adult onset neurodegenerative disorder worldwide. It is generally characterized by progressive paralysis starting at the limbs ultimately leading to death caused...
8.
Cobos S, Bennett S, Torrente M
Biochim Biophys Acta Mol Basis Dis . 2018 Oct; 1865(8):1982-1991. PMID: 30352259
Every year, neurodegenerative disorders take more than 5000 lives in the US alone. Cures have not yet been found for many of the multitude of neuropathies. The majority of amyotrophic...
9.
Chen K, Bennett S, Rana N, Yousuf H, Said M, Taaseen S, et al.
ACS Chem Neurosci . 2017 Dec; 9(4):838-848. PMID: 29243911
Amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) are devastating neurodegenerative diseases involving the progressive degeneration of neurons. No cure is available for patients diagnosed with these diseases. A prominent...