Sergio Madurga
Overview
Explore the profile of Sergio Madurga including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
371
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Recent Articles
1.
Gorria T, Sierra-Boada M, Rojas M, Figueras C, Marin S, Madurga S, et al.
Cancers (Basel)
. 2025 Feb;
17(3).
PMID: 39941865
Although immune checkpoint inhibitor (ICI) therapy is currently the standard of care in microsatellite-unstable (MSI) metastatic colorectal cancer (CRC), ICI therapy, alone or in combination with other therapies, is not...
2.
Orradre J, Blanco P, Madurga S, Mas F, Garces J
J Chem Phys
. 2024 Nov;
161(20).
PMID: 39588833
Conformational and ionization equilibria of flexible weak polyelectrolytes (PEs) are, in general, strongly coupled. In this article, we analyze the effect of averaging over (or "contracting") the conformational degrees of...
3.
Sanchez-Garcia S, Povo-Retana A, Marin S, Madurga S, Farinas M, Aleixandre N, et al.
Adv Healthc Mater
. 2024 Nov;
14(1):e2401688.
PMID: 39502019
The cytokine storm associated with SARS-CoV-2 infection is one of the most distinctive pathological signatures in COVID-19 patients. Macrophages respond to this pro-inflammatory challenge by reprogramming their functional and metabolic...
4.
Saranjam L, Nedyalkova M, Fuguet E, Simeonov V, Mas F, Madurga S
Molecules
. 2023 Aug;
28(15).
PMID: 37570699
This study focuses on determining the partition coefficients (logP) of a diverse set of 63 molecules in three distinct micellar systems: hexadecyltrimethylammonium bromide (HTAB), sodium cholate (SC), and lithium perfluorooctanesulfonate...
5.
Blanco P, Narambuena C, Madurga S, Mas F, Garces J
Polymers (Basel)
. 2023 Jun;
15(12).
PMID: 37376324
This article reviews the state of the art of the studies on charge regulation (CR) effects in flexible weak polyelectrolytes (FWPE). The characteristic of FWPE is the strong coupling of...
6.
Privat C, Madurga S, Mas F, Rubio-Martinez J
Phys Chem Chem Phys
. 2022 Aug;
24(31):18841-18853.
PMID: 35912724
For the discovery of treatments against synucleinopathies, it is necessary to unravel and fully understand the mechanism of fibrillation of proteins involved. Among them, α-synuclein (αS) plays a key role...
7.
Blanco P, Achetoni M, Garces J, Madurga S, Mas F, Baieli M, et al.
Colloids Surf B Biointerfaces
. 2022 Jun;
217:112617.
PMID: 35738075
We analyze the conditions of the adsorption of a flexible peptide onto a charged substrate in the 'wrong side' of the isoelectric point (WSIP), i.e. when surface and peptide charges...
8.
Nedyalkova M, Vasighi M, Sappati S, Kumar A, Madurga S, Simeonov V
Pharmaceuticals (Basel)
. 2021 Dec;
14(12).
PMID: 34959727
The lack of medication to treat COVID-19 is still an obstacle that needs to be addressed by all possible scientific approaches. It is essential to design newer drugs with varied...
9.
Barazorda-Ccahuana H, Nedyalkova M, Mas F, Madurga S
Polymers (Basel)
. 2021 Nov;
13(21).
PMID: 34771379
(1) Background: Main Protease (Mpro) is an attractive therapeutic target that acts in the replication and transcription of the SARS-CoV-2 coronavirus. Mpro is rich in residues exposed to protonation/deprotonation changes...
10.
Privat C, Madurga S, Mas F, Rubio-Martinez J
Polymers (Basel)
. 2021 Oct;
13(19).
PMID: 34641127
An accurate description of the protonation state of amino acids is essential to correctly simulate the conformational space and the mechanisms of action of proteins or other biochemical systems. The...