Sergio Linsambarth
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Explore the profile of Sergio Linsambarth including associated specialties, affiliations and a list of published articles.
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9
Citations
74
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Recent Articles
1.
Puebla-Huerta A, Huerta H, Quezada-Gutierez C, Morgado-Caceres P, Casanova-Canelo C, Nino S, et al.
NPJ Aging
. 2025 Feb;
11(1):11.
PMID: 39984524
Therapy-induced senescence (TIS) alters calcium (Ca²⁺) flux and Mitochondria-ER Contact Sites (MERCS), revealing critical vulnerabilities in senescent cells. In this study, TIS was induced using Doxorubicin and Etoposide, resulting in...
2.
Duarte Y, Quintana-Donoso D, Moraga-Amaro R, Dinamarca I, Lemunao Y, Cardenas K, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(46):e2307953121.
PMID: 39495924
The role of ventral hippocampus (vHipp) astroglial gliotransmission in depression was studied using chronic restraint stress (CRS) and chronic unpredictable mild stress (CUMS) rodent models. CRS increased Cx43 hemichannel activity...
3.
Bahamonde T, Quintana-Donoso D, Linsambarth S, Jerez-Baraona J, Pena F, Tamburini G, et al.
Neuropharmacology
. 2023 Jun;
237:109620.
PMID: 37263575
Increased activity in the insula has been consistently reported to be associated with anxiety and anxiety-related disorders. However, little is known on how the insula regulates anxiety. The present study...
4.
Moraga-Amaro R, Munoz P, Villalobos T, Linsambarth S, Maldonado F, Meirone V, et al.
Psychiatry Res
. 2022 Dec;
320:115036.
PMID: 36586377
Activation of the insula is found in all anxiety-related disorders and increased insular-prefrontal cortex (PFC) functional connectivity is associated with reduced anxiety. In this study, the combined stimulation of the...
5.
Linsambarth S, Carvajal F, Moraga-Amaro R, Mendez L, Tamburini G, Jimenez I, et al.
FASEB J
. 2022 Jan;
36(2):e22134.
PMID: 35061296
Astrocytes release gliotransmitters via connexin 43 (Cx43) hemichannels into neighboring synapses, which can modulate synaptic activity and are necessary for fear memory consolidation. However, the gliotransmitters released, and their mechanisms...
6.
Moraga-Amaro R, Diaz-Galarce R, Donoso-Ramos J, Ugalde V, Linsambarth S, Doorduin J, et al.
Neuropharmacology
. 2021 Aug;
197:108751.
PMID: 34375626
Fluoxetine is often prescribed to treat depression during pregnancy. Rodent studies have shown that fluoxetine exposure during early development can induce persistent changes in the emotional behavior of the offspring....
7.
Retamal M, Fiori M, Fernandez-Olivares A, Linsambarth S, Pena F, Quintana D, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2020 Apr;
1865(8):158705.
PMID: 32244060
Hemichannels formed by connexins mediate the exchange of ions and signaling molecules between the cytoplasm and the extracellular milieu. Under physiological conditions hemichannels have a low open probability, but in...
8.
Linsambarth S, Jeria A, Avirame K, Todder D, Riquelme R, Stehberg J
J ECT
. 2019 Nov;
35(4):e46-e54.
PMID: 31764455
Background: Negative symptoms of schizophrenia show limited response to both typical and atypical antipsychotics. Repetitive transcranial magnetic stimulation applied over the prefrontal cortex (PFC) has been proposed as an adjuvant...
9.
Mendez-Ruette M, Linsambarth S, Moraga-Amaro R, Quintana-Donoso D, Mendez L, Tamburini G, et al.
Front Physiol
. 2019 Apr;
10:330.
PMID: 30984021
The human insula has been consistently reported to be overactivated in all anxiety disorders, activation which has been suggested to be proportional to the level of anxiety and shown to...
10.
Torres F, Villalon E, Poblete P, Moraga-Amaro R, Linsambarth S, Riquelme R, et al.
Front Neurol
. 2015 Nov;
6:210.
PMID: 26579065
Objective: To evaluate the safety and assess the different symptom improvements found after a combined low-frequency primary motor cortex and high-frequency prefrontal cortex (PFC) stimulation using the deep TMS (dTMS)...