Sergey Nejentsev
Overview
Explore the profile of Sergey Nejentsev including associated specialties, affiliations and a list of published articles.
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52
Citations
4734
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Recent Articles
1.
Seidelin J, Jensen S, Hansen M, de Carvalho Bronze M, Cuchet-Loureno D, Nejentsev S, et al.
Clin Exp Immunol
. 2023 Aug;
215(3):291-301.
PMID: 37583360
Innate immune activity fuels intestinal inflammation in Crohn's disease (CD), an inflammatory bowel disease. Identification and targeting of new molecular regulators of the innate activity are warranted to control the...
2.
Begg M, Amour A, Jarvis E, Tang T, Franco S, Want A, et al.
Pulm Pharmacol Ther
. 2023 Feb;
79:102201.
PMID: 36841351
Activated PI3Kδ Syndrome (APDS) is a rare inherited inborn error of immunity caused by mutations that constitutively activate the p110 delta isoform of phosphoinositide 3-kinase (PI3Kδ), resulting in recurring pulmonary...
3.
Papapietro O, Nejentsev S
Front Immunol
. 2022 Sep;
13:982870.
PMID: 36045673
Topoisomerase 2β (TOP2B) introduces transient double strand breaks in the DNA helix to remove supercoiling structures and unwind entangled DNA strains. Advances in genomic technologies have enabled the discovery of...
4.
Ouahed J, Kelsen J, Spessott W, Kooshesh K, Sanmillan M, Dawany N, et al.
J Crohns Colitis
. 2021 Apr;
15(11):1908-1919.
PMID: 33891011
Background And Aims: Very early onset inflammatory bowel disease [VEOIBD] is characterized by intestinal inflammation affecting infants and children less than 6 years of age. To date, over 60 monogenic...
5.
Meijers A, Troost R, Ummels R, Maaskant J, Speer A, Nejentsev S, et al.
Tuberculosis (Edinb)
. 2020 Aug;
124:101983.
PMID: 32829077
The ability to genetically engineer pathogenic mycobacteria has increased significantly over the last decades due to the generation of new molecular tools. Recently, the application of the Streptococcus pyogenes and...
6.
Papapietro O, Chandra A, Eletto D, Inglott S, Plagnol V, Curtis J, et al.
Blood
. 2020 Mar;
135(17):1497-1501.
PMID: 32128574
No abstract available.
7.
Luo Y, Suliman S, Asgari S, Amariuta T, Baglaenko Y, Martinez-Bonet M, et al.
Nat Commun
. 2019 Aug;
10(1):3765.
PMID: 31434886
Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5-15% will develop active tuberculosis (TB). Approximately half will progress to active TB within the first 18 months after infection,...
8.
Goos H, Fogarty C, Sahu B, Plagnol V, Rajamaki K, Nurmi K, et al.
J Allergy Clin Immunol
. 2019 Jun;
144(5):1364-1376.
PMID: 31201888
Background: CCAAT enhancer-binding protein epsilon (C/EBPε) is a transcription factor involved in late myeloid lineage differentiation and cellular function. The only previously known disorder linked to C/EBPε is autosomal recessive...
9.
Farela Neves J, Doffinger R, Barcena-Morales G, Martins C, Papapietro O, Plagnol V, et al.
Front Immunol
. 2019 Jan;
9:2863.
PMID: 30619256
The auto-inflammation and phospholipase Cγ2 (PLCγ2)-associated antibody deficiency and immune dysregulation (APLAID) syndrome is a rare primary immunodeficiency caused by a gain-of-function mutation S707Y in the gene previously described in...
10.
Tylee D, Sun J, Hess J, Tahir M, Sharma E, Malik R, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2018 Oct;
177(7):641-657.
PMID: 30325587
Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and altered immune signaling. It is unclear whether these altered immunological states have a shared genetic basis with those psychiatric...