Serena Marcelli
Overview
Explore the profile of Serena Marcelli including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
142
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0
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Recent Articles
1.
Marcelli S, Iannuzzi F, Ficulle E, Mango D, Pieraccini S, Pellegrino S, et al.
Sci Rep
. 2019 May;
9(1):7146.
PMID: 31073146
The neuronal loss caused by excessive glutamate release, or 'excitotoxicity', leads to several pathological conditions, including cerebral ischemia, epilepsy, and neurodegenerative diseases. Over-stimulation of presynaptic N-methyl-D-aspartate (NMDA) receptors is known...
2.
Tinelli C, Di Pino A, Ficulle E, Marcelli S, Feligioni M
Front Nutr
. 2019 May;
6:49.
PMID: 31069230
Hyperhomocysteinemia is recognized as a risk factor for several diseases, including cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite involved in the biosynthesis and metabolism of methionine (Met),...
3.
Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, et al.
Exp Neurol
. 2019 Mar;
317:51-65.
PMID: 30822420
In mammals, free d-aspartate (D-Asp) is abundant in the embryonic brain, while levels remain very low during adulthood as a result of the postnatal expression and activity of the catabolizing...
4.
Marcelli S, Corbo M, Iannuzzi F, Negri L, Blandini F, Nistico R, et al.
Curr Alzheimer Res
. 2017 May;
15(4):313-335.
PMID: 28474569
Background: Alzheimer's disease (AD) is a neurodegenerative disorder recognized as the most common cause of chronic dementia among the ageing population. AD is histopathologically characterized by progressive loss of neurons...
5.
Marcelli S, Ficulle E, Iannuzzi F, Kovari E, Nistico R, Feligioni M
Mol Neurobiol
. 2016 Oct;
54(8):6609-6623.
PMID: 27738871
Synaptic dysfunction has been recognized as an early feature occurring at the onset of Alzheimer's disease (AD). Compromised neurotransmission leads over time to synaptic loss and these events correlate with...