Seong-Jin Yu
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Explore the profile of Seong-Jin Yu including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
481
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Recent Articles
1.
Chiu Y, Wu K, Yu S, Wu K, Hsieh C, Chou Y, et al.
Cell Transplant
. 2024 Dec;
33:9636897241296366.
PMID: 39624898
Cerebral ischemic stroke is a major cerebrovascular disease and the leading cause of adult disability. We and others previously demonstrated that transplantation of human Wharton's jelly mesenchymal stromal cells (WJ-MSCs)...
2.
Yu S, Wu K, Wang Y, Bae E, Chianelli F, Bambakidis N, et al.
BMC Neurosci
. 2024 Oct;
25(1):49.
PMID: 39379834
Background: Psilocybin is a psychedelic 5HT2A receptor agonist found in "magic mushrooms". Recent studies have indicated that 5HT2A agonists, such as dimethyltryptamine, given before middle cerebral artery occlusion (MCAo), improve...
3.
Yu S, Wang Y, Shen H, Bae E, Li Y, Sambamurti K, et al.
Geroscience
. 2024 Apr;
46(5):4349-4371.
PMID: 38563864
Epidemiological studies report an elevated risk of Parkinson's disease (PD) in patients with type 2 diabetes mellitus (T2DM) that is mitigated in those prescribed dipeptidyl peptidase 4 (DPP-4) inhibitors. With...
4.
Li Y, Vaughan K, Wang Y, Yu S, Bae E, Tamargo I, et al.
Geroscience
. 2024 Mar;
46(5):4397-4414.
PMID: 38532069
The endogenous incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) possess neurotrophic, neuroprotective, and anti-neuroinflammatory actions. The dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin reduces degradation of endogenous GLP-1 and...
5.
Chiu Y, Wu K, Yu S, Wu K, Wang Y, Lin J, et al.
PLoS One
. 2023 Sep;
18(9):e0291927.
PMID: 37733672
Abnormal accumulation of alpha-synuclein (αSyn) in the remaining nigra dopaminergic neurons is a common neuropathological feature found in patients with Parkinson's disease (PD). Antibody-based immunotherapy has been considered a potential...
6.
Wu K, Hung T, Wang Y, Chen Y, Bae E, Yu S
Sci Rep
. 2023 May;
13(1):8148.
PMID: 37208379
Saposin and its precursor prosaposin are endogenous proteins with neurotrophic and anti-apoptotic properties. Prosaposin or its analog prosaposin-derived 18-mer peptide (PS18) reduced neuronal damage in hippocampus and apoptosis in stroke...
7.
Wu K, Wang Y, Hung T, Bae E, Chen Y, Kim C, et al.
PLoS One
. 2023 Feb;
18(2):e0281421.
PMID: 36812289
Stroke is a major cause of long-term disability world-wide. Limited pharmacological therapy has been used in stroke patients. Previous studies indicated that herb formula PM012 is neuroprotective against neurotoxin trimethyltin...
8.
Chen S, Chen H, Yu S, Chen Y, Wang Y
Cell Transplant
. 2021 Nov;
30:9636897211052300.
PMID: 34743572
Amphetamine-type stimulants have become important and popular abused drugs worldwide. Methamphetamine (Meth) sensitization, characterized by a progressive increase in behavioral responses after repeated administration, has been reported in rodents and...
9.
Hung T, Wu K, Wang Y, Bae E, Song Y, Yoon J, et al.
Int J Mol Sci
. 2021 Sep;
22(18).
PMID: 34576050
Intracerebral hemorrhage (ICH) occurs when brain blood vessels rupture, causing inflammation and cell death. 2-Fucosyllactose (2FL), a human milk oligosaccharide, has potent antiapoptotic and anti-inflammatory effects. The purpose of this...
10.
Chen Y, Wu K, Hsieh W, Harvey B, Hoffer B, Wang Y, et al.
Genes (Basel)
. 2021 Jul;
12(6).
PMID: 34205689
Accumulation of α-Synuclein (αSyn) in nigral dopaminergic neurons is commonly seen in patients with Parkinson's disease (PD). We recently reported that transduction of intracellular single-chain intrabody targeting the 53-87 amino...