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Senaka Rajapakse

Explore the profile of Senaka Rajapakse including associated specialties, affiliations and a list of published articles. Areas
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Articles 121
Citations 1520
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Recent Articles
1.
Moallemi S, Tedla N, Sigera C, Weeratunga P, Fernando D, Rajapakse S, et al.
J Infect . 2025 Jan; 90(2):106401. PMID: 39756695
Background: Dengue, a mosquito-borne viral infection, poses a rapidly growing burden, particularly in low- and middle-income countries. Without early identification of patients at risk of severe outcomes (dengue haemorrhagic fever,...
2.
Gangani D, Dissanayake W, de Silva R, Anuradha K, Karunanayake L, Fernando N, et al.
BMC Immunol . 2023 Oct; 24(1):39. PMID: 37848809
Background: Leptospirosis is a zoonotic disease caused by Leptospira species. Variations in lipopolysaccharide (LPS) structure in Leptospira are known to be associated with the serovar diversity and antigenicity. Development of...
3.
Maduranga S, Valencia B, Sigera C, Adikari T, Weeratunga P, Fernando D, et al.
Viruses . 2023 Jul; 15(7). PMID: 37515097
All four serotypes of the dengue virus (DENV1-4) cause a phenotypically similar illness, but serial infections from different serotypes increase the risk of severe disease. Thus, genomic surveillance of circulating...
4.
Wickramasinghe W, Alvitigala B, Perera T, Karunanayake P, Jayasinghe S, Rajapakse S, et al.
Platelets . 2023 Jun; 34(1):2229909. PMID: 37370234
Citrate is widely used as an anticoagulant for platelet function tests (PFTs). Due to an intrinsic inhibitory effect of citrate on platelet function, hirudin is used as an alternative. However,...
5.
Zargari Marandi R, Leung P, Sigera C, Murray D, Weeratunga P, Fernando D, et al.
PLoS Negl Trop Dis . 2023 Mar; 17(3):e0010758. PMID: 36913411
Background: At least a third of dengue patients develop plasma leakage with increased risk of life-threatening complications. Predicting plasma leakage using laboratory parameters obtained in early infection as means of...
6.
Valencia B, Sigera P, Weeratunga P, Tedla N, Fernando D, Rajapakse S, et al.
Sci Rep . 2022 Oct; 12(1):17225. PMID: 36241869
Given the structural similarity between Zika and dengue viruses, prior infection from one virus is hypothesized to modulate the severity of a subsequent infection from the other virus. A previous...
7.
Rodrigo C, Herath T, Wickramarachchi U, Fernando D, Rajapakse S
Trans R Soc Trop Med Hyg . 2022 Jun; 116(10):889-899. PMID: 35666998
Post-chikungunya joint pain (arthritis or arthralgia) is a clinical concern in endemic regions as it may cause a debilitating illness sometimes years after the acute infection. This systematic review analyses...
8.
Wickramasinghe W, Alvitigala B, Perera T, Karunanayake P, Jayasinghe S, Rajapakse S, et al.
Res Pract Thromb Haemost . 2022 Apr; 6(3):e12704. PMID: 35475291
Background: The critical phase of dengue carries a high risk of bleeding. Associations of coagulation test parameters and the risk of bleeding in the critical phase is unclear. This study...
9.
Rajapakse S
Clin Med (Lond) . 2022 Jan; 22(1):14-17. PMID: 35078790
Leptospirosis is one of the most important zoonotic bacterial diseases worldwide, commonly affecting resource-poor populations and resulting in significant morbidity and mortality. This article provides an overview of the epidemiology,...
10.
Rodrigo C, Sigera C, Fernando D, Rajapakse S
BMC Infect Dis . 2021 Oct; 21(1):1082. PMID: 34670495
Plasma leakage is a precursor to life-threatening complications of dengue, but this group is poorly defined and not often reported in literature. Patients with Dengue haemorrhagic fever (DHF) as defined...