Selene Ferrari
Overview
Explore the profile of Selene Ferrari including associated specialties, affiliations and a list of published articles.
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10
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727
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Recent Articles
1.
Borah S, Shivarathri R, Srivastava V, Ferrari S, Sanglard D, Kaur R
Antimicrob Agents Chemother
. 2014 Jul;
58(10):5976-86.
PMID: 25070095
Antifungal therapy failure can be associated with increased resistance to the employed antifungal agents. Candida glabrata, the second most common cause of invasive candidiasis, is intrinsically less susceptible to the...
2.
Vandeputte P, Pradervand S, Ischer F, Coste A, Ferrari S, Harshman K, et al.
Eukaryot Cell
. 2012 May;
11(7):916-31.
PMID: 22581526
The identification of novel transcription factors associated with antifungal response may allow the discovery of fungus-specific targets for new therapeutic strategies. A collection of 241 Candida albicans transcriptional regulator mutants...
3.
Vandeputte P, Ferrari S, Coste A
Int J Microbiol
. 2011 Dec;
2012:713687.
PMID: 22187560
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of antifungal resistance is still of major concern in clinical practice. In the last 10 years the molecular...
4.
Florio A, Ferrari S, De Carolis E, Torelli R, Fadda G, Sanguinetti M, et al.
BMC Microbiol
. 2011 May;
11:97.
PMID: 21569340
Background: Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined...
5.
Ferrari S, Sanguinetti M, Torelli R, Posteraro B, Sanglard D
PLoS One
. 2011 Mar;
6(3):e17589.
PMID: 21408004
In Candida glabrata, the transcription factor CgPdr1 is involved in resistance to azole antifungals via upregulation of ATP binding cassette (ABC)-transporter genes including at least CgCDR1, CgCDR2 and CgSNQ2. A...
6.
Ferrari S, Sanguinetti M, De Bernardis F, Torelli R, Posteraro B, Vandeputte P, et al.
Antimicrob Agents Chemother
. 2011 Feb;
55(5):1852-60.
PMID: 21321146
Mitochondrial dysfunction is one of the possible mechanisms by which azole resistance can occur in Candida glabrata. Cells with mitochondrial DNA deficiency (so-called "petite mutants") upregulate ATP binding cassette (ABC)...
7.
Sanglard D, Coste A, Ferrari S
FEMS Yeast Res
. 2009 Oct;
9(7):1029-50.
PMID: 19799636
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution. Some fungal species may interact with other life forms (plants, insects, mammals), but are considered as...
8.
Ferrari S, Ischer F, Calabrese D, Posteraro B, Sanguinetti M, Fadda G, et al.
PLoS Pathog
. 2009 Jan;
5(1):e1000268.
PMID: 19148266
CgPdr1p is a Candida glabrata Zn(2)-Cys(6) transcription factor involved in the regulation of the ABC-transporter genes CgCDR1, CgCDR2, and CgSNQ2, which are mediators of azole resistance. Single-point mutations in CgPDR1...
9.
Torelli R, Posteraro B, Ferrari S, La Sorda M, Fadda G, Sanglard D, et al.
Mol Microbiol
. 2008 Mar;
68(1):186-201.
PMID: 18312269
Our previous investigation on Candida glabrata azole-resistant isolates identified two isolates with unaltered expression of CgCDR1/CgCDR2, but with upregulation of another ATP-binding cassette transporter, CgSNQ2, which is a gene highly...
10.
Ferrari S, Simmen K, Dusserre Y, Muller K, Fourel G, Gilson E, et al.
J Biol Chem
. 2004 Oct;
279(53):55520-30.
PMID: 15471882
When located next to chromosomal elements such as telomeres, genes can be subjected to epigenetic silencing. In yeast, this is mediated by the propagation of the SIR proteins from telomeres...