Sebastien Vallee
Overview
Explore the profile of Sebastien Vallee including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
192
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Recent Articles
1.
Yang J, Toughiri R, Gounder A, Scheibe D, Petrus M, Fink S, et al.
PLoS One
. 2024 Nov;
19(11):e0307049.
PMID: 39504332
Induction of fetal hemoglobin (HbF) has been shown to be a viable therapeutic approach to treating sickle cell disease and potentially other β-hemoglobinopathies. To identify targets and target-modulating small molecules...
2.
Kawakami E, Saiki N, Yoneyama Y, Moriya C, Maezawa M, Kawamura S, et al.
Cell Stem Cell
. 2023 Oct;
30(10):1315-1330.e10.
PMID: 37802037
COVID-19 is linked to endotheliopathy and coagulopathy, which can result in multi-organ failure. The mechanisms causing endothelial damage due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain elusive. Here,...
3.
Gross O, Kashtan C, Rheault M, Flinter F, Savige J, Miner J, et al.
Nephrol Dial Transplant
. 2016 May;
32(6):916-924.
PMID: 27190345
Alport syndrome (AS) is a genetic disease characterized by haematuric glomerulopathy variably associated with hearing loss and anterior lenticonus. It is caused by mutations in the COL4A3, COL4A4 or COL4A5...
4.
Vallee S, Rakhe S, Reidy T, Walker S, Lu Q, Sakorafas P, et al.
J Interferon Cytokine Res
. 2011 Dec;
32(4):178-84.
PMID: 22191463
Currently, products containing interferon beta (IFNβ) are injected either intramuscularly or subcutaneously. To avoid the necessity of injection, we developed a novel monomeric Fc fusion protein of IFNβ (IFNβFc) that...
5.
Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling
Fu G, Vallee S, Rybakin V, McGuire M, Ampudia J, Brockmeyer C, et al.
Nat Immunol
. 2009 Jul;
10(8):848-56.
PMID: 19597499
Themis (thymocyte-expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis had high expression in...
6.
Vallee S, Laforest S, Fouchier F, Montero M, Penel C, Champion S
Exp Cell Res
. 2004 Jun;
297(1):165-85.
PMID: 15194434
As described for a long time, carcinoma-derived Caco-2 cells form a polarized epithelium in culture, whereas HT29-D4 cells are nonpolarized and undifferentiated but can form a polarized monolayer when cultured...
7.
Chen Y, Vallee S, Wu J, Vu D, Sondek J, Ghosh G
Mol Cell Biol
. 2004 Mar;
24(7):3048-56.
PMID: 15024091
IkappaBbeta, one of the major IkappaB proteins, is only partially degraded in response to most extracellular signals. However, the molecular mechanism of this event is unknown. We show here that...
8.
Vallee S, Fouchier F, Bremond P, Briand C, Marvaldi J, Champion S
Biochem Biophys Res Commun
. 2003 May;
305(4):831-9.
PMID: 12767906
Pretreatment of HT29-D4 epithelial adenocarcinoma colic cells with des-IGF-1 upregulated TNF alpha-mediated activation of IL-8 expression at different levels (protein, mRNA, and hnRNA). RNA transcription but not RNA stabilization was...