Sebastien Nouaille
Overview
Explore the profile of Sebastien Nouaille including associated specialties, affiliations and a list of published articles.
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23
Citations
386
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Recent Articles
1.
Roux C, Ramos-Hue M, Audonnet M, Duviau M, Nouaille S, Carpousis A, et al.
mBio
. 2024 Nov;
16(1):e0268024.
PMID: 39611689
The post-transcriptional process of RNA polyadenylation sits at the crossroads of energy metabolism and RNA metabolism. RNA polyadenylation is catalyzed by poly(A) polymerases, which use ATP as a substrate to...
2.
Anny C, Nouaille S, Faure R, Schulz C, Spriet C, Huvent I, et al.
Curr Protoc
. 2024 Mar;
4(3):e1016.
PMID: 38511507
Investigating the function of target proteins for functional prospection or therapeutic applications typically requires the production and purification of recombinant proteins. The fusion of these proteins with tag peptides and...
3.
Duviau M, Chen F, Emile A, Cocaign-Bousquet M, Girbal L, Nouaille S
Nucleic Acids Res
. 2023 Feb;
51(6):2877-2890.
PMID: 36840715
mRNA sits at the crossroads of transcription, translation and mRNA degradation. Many questions remain about the coupling of these three processes in Escherichia coli and, in particular, how translation may...
4.
Chen F, Cocaign-Bousquet M, Girbal L, Nouaille S
Front Microbiol
. 2023 Jan;
13:1088941.
PMID: 36620028
A set of 41 synthetic 5'UTRs with different theoretical translation initiation rates were generated to explore the role of 5'UTRs in the regulation of protein levels in . The roles...
5.
Laroute V, Beaufrand C, Gomes P, Nouaille S, Tondereau V, Daveran-Mingot M, et al.
Elife
. 2022 Jun;
11.
PMID: 35727704
Gut disorders associated to irritable bowel syndrome (IBS) are combined with anxiety and depression. Evidence suggests that microbially produced neuroactive molecules, like γ-aminobutyric acid (GABA), can modulate the gut-brain axis....
6.
Nguyen H, Duviau M, Laguerre S, Nouaille S, Cocaign-Bousquet M, Girbal L
Microbiol Spectr
. 2022 Feb;
10(1):e0204121.
PMID: 35138139
Translational regulation was investigated at the genome-scale in Escherichia coli cells. Using the polysome profiling method, the ribosome occupancy (RO) and ribosome density (RD) of different mRNA copies were determined...
7.
Pelus A, Bordes G, Barbe S, Bouchiba Y, Burnard C, Cortes J, et al.
Biomater Sci
. 2021 Oct;
9(22):7444-7455.
PMID: 34647546
The development of protein and microorganism engineering have led to rising expectations of biotechnology in the design of emerging biomaterials, putatively of high interest to reduce our dependence on fossil...
8.
Nguyen H, Duviau M, Cocaign-Bousquet M, Nouaille S, Girbal L
PLoS One
. 2019 Feb;
14(2):e0212297.
PMID: 30779773
Polysome profiling is a widely used method to monitor the translation status of mRNAs. Although it is theoretically a simple technique, it is labor intensive. Repetitive polysome fractionation rapidly generates...
9.
Laguerre S, Gonzalez I, Nouaille S, Moisan A, Villa-Vialaneix N, Gaspin C, et al.
Methods Enzymol
. 2018 Dec;
612:47-66.
PMID: 30502954
In this study, we compared different computational methods used for genome-wide determination of mRNA half-lives in Escherichia coli with a special focus on the impact on considering a delay before...
10.
Nouaille S, Mondeil S, Finoux A, Moulis C, Girbal L, Cocaign-Bousquet M
Nucleic Acids Res
. 2017 Oct;
45(20):11711-11724.
PMID: 28977619
Changing mRNA stability is a major post-transcriptional way of controlling gene expression, particularly in newly encountered conditions. As the concentration of mRNA is the result of an equilibrium between transcription...