Sebastien Gouard
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Explore the profile of Sebastien Gouard including associated specialties, affiliations and a list of published articles.
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32
Citations
401
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Recent Articles
1.
Lugat A, Chouin N, Chocteau F, Esnault M, Marionneau-Lambot S, Gouard S, et al.
Eur J Nucl Med Mol Imaging
. 2024 Sep;
52(2):730-743.
PMID: 39269657
Methods: A mouse model of liver metastases of pancreatic NETs was developed by intraportal injection of AR42J cells and explored using [ Ga]Ga-DOTATOC and [F]F-FDG PET/MRI. Biodistribution study and radiation...
2.
Roncali L, Marionneau-Lambot S, Roy C, Eychenne R, Gouard S, Avril S, et al.
EBioMedicine
. 2024 Jun;
105:105202.
PMID: 38905749
Background: Glioblastoma (GB), the most aggressive brain cancer, remains a critical clinical challenge due to its resistance to conventional treatments. Here, we introduce a locoregional targeted-α-therapy (TAT) with the rat...
3.
Taheri N, Le Crom B, Bouillot C, Cherel M, Costes N, Gouard S, et al.
Phys Med Biol
. 2023 Mar;
68(8).
PMID: 36958048
Using different tracers in positron emission tomography (PET) imaging can bring complementary information on tumor heterogeneities. Ideally, PET images of different tracers should be acquired simultaneously to avoid the bias...
4.
Delage J, Gnesin S, Prior J, Barbet J, Saec P, Marionneau-Lambot S, et al.
Cancers (Basel)
. 2021 Dec;
13(23).
PMID: 34885044
1C1m-Fc, a promising anti-TEM-1 DOTA conjugate, was labeled with Cu to target cancer cells for PET imaging and predicting the efficacy and safety of a previously studied [Lu]Lu-1C1m-Fc companion therapy....
5.
Perrin J, Capitao M, Allard M, Chouin N, Gouard S, Marionneau-Lambot S, et al.
Int J Radiat Oncol Biol Phys
. 2021 Oct;
112(3):790-801.
PMID: 34699930
Purpose: The tumor microenvironment (TME) can severely impair immunotherapy efficacy by repressing the immune system. In a multiple myeloma (MM) murine model, we investigated the impact of targeted alpha particle...
6.
Berdal M, Gouard S, Eychenne R, Marionneau-Lambot S, Croyal M, Faivre-Chauvet A, et al.
Chem Sci
. 2021 Jun;
12(4):1458-1468.
PMID: 34163909
Easy access to radioiodinated and At-labelled bio(macro)molecules is essential to develop new strategies in nuclear imaging and targeted radionuclide therapy of cancers. Yet, the labelling of complex molecules with heavy...
7.
Capitao M, Perrin J, Simon S, Gouard S, Chouin N, Bruchertseifer F, et al.
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33809167
PD-L1 (programmed death-ligand 1, B7-H1, CD274), the ligand for PD-1 inhibitory receptor, is expressed on various tumors, and its expression is correlated with a poor prognosis in melanoma. Anti-PD-L1 mAbs...
8.
Gouard S, Maurel C, Marionneau-Lambot S, Dansette D, Bailly C, Guerard F, et al.
Cancers (Basel)
. 2020 Sep;
12(9).
PMID: 32971984
Despite therapeutic progress in recent years with the introduction of targeted therapies (daratumumab, elotuzumab), multiple myeloma remains an incurable cancer. The question is therefore to investigate the potential of targeted...
9.
Bailly C, Chalopin B, Gouard S, Carlier T, Saec P, Marionneau-Lambot S, et al.
Cancers (Basel)
. 2020 Jun;
12(6).
PMID: 32512883
Despite constant progress over the past three decades, multiple myeloma (MM) is still an incurable disease, and the identification of new biomarkers to better select patients and adapt therapy is...
10.
Leonetti D, Estephan H, Ripoche N, Dubois N, Aguesse A, Gouard S, et al.
Cancer Res
. 2020 Apr;
80(12):2651-2662.
PMID: 32291318
Ceramide-induced endothelial cell apoptosis boosts intestinal stem cell radiosensitivity. However, the molecular connection between these two cellular compartments has not been clearly elucidated. Here we report that ceramide and its...