Sebastiano Macheda
Overview
Explore the profile of Sebastiano Macheda including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
166
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0
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Recent Articles
1.
Panuccio G, Correale P, dApolito M, Mutti L, Giannicola R, Pirtoli L, et al.
Basic Res Cardiol
. 2024 Sep;
120(1):153-169.
PMID: 39225869
Immunotherapy represents an emergent and heterogeneous group of anticancer treatments harnessing the human immune-surveillance system, including immune-checkpoint inhibitor monoclonal antibodies (mAbs), Chimeric Antigen Receptor T Cells (CAR-T) therapy, cancer vaccines...
2.
Bruni A, Longhini F, Macheda S, Biamonte E, Pasqua P, Neri G, et al.
Front Med (Lausanne)
. 2022 Dec;
9:1042411.
PMID: 36507545
Introduction: After the rapid surge of a novel coronavirus (SARS-CoV-2) in 2020 anti-SARS-CoV-2 vaccines have been developed to prevent the development of critical forms of COVID-19 leading to Intensive Care...
3.
Garofalo E, Cammarota G, Neri G, Macheda S, Biamonte E, Pasqua P, et al.
J Clin Med
. 2022 Oct;
11(20).
PMID: 36294312
(1) Background: In COVID-19 patients, the occurrence of thromboembolic complications contributes to disease progression and mortality. In patients at increased risk for thrombotic complications, therapeutic enoxaparin should be considered. However,...
4.
Martino M, Macheda S, Aguglia U, Arcudi L, Pucci G, Martino B, et al.
Expert Opin Biol Ther
. 2021 Aug;
22(3):407-421.
PMID: 34463175
Introduction: Chimeric antigen receptor (CAR)-T-cell therapy is a new treatment for patients with hematologic malignancies in which other therapies have failed. Areas Covered: The review provides an overview for recognizing...
5.
Nardone V, Giannicola R, Bianco G, Giannarelli D, Tini P, Pastina P, et al.
Front Oncol
. 2021 Jul;
11:684110.
PMID: 34195086
Peripheral-immune-checkpoint blockade (P-ICB) with mAbs to PD-1 (nivolumab and pembrolizumab) or PD-L1 (atezolizumab, durvalumab, avelumab) alone or combination with chemotherapy represents a novel active treatment for mNSCLC patients. However, this...
6.
Tescione M, Vadala E, Marano G, Battaglia E, Bruni A, Garofalo E, et al.
J Clin Monit Comput
. 2021 May;
36(3):823-828.
PMID: 33956283
Surgery for hip fractures should be performed within 48 h from patient's admission. However, several factors including chronic antiplatelet therapy could delay operation. Among the totality of patients taking clopidogrel,...
7.
Caracciolo M, Correale P, Mangano C, Foti G, Falcone C, Macheda S, et al.
Front Immunol
. 2021 Apr;
12:613070.
PMID: 33815368
Lack of specific antiviral treatment for COVID-19 has resulted in long hospitalizations and high mortality rate. By harnessing the regulatory effects of adenosine on inflammatory mediators, we have instituted a...
8.
Tescione M, Vadala E, Marano G, Bruni A, Garofalo E, Lavalle O, et al.
Clin Case Rep
. 2021 Mar;
9(3):1049-1054.
PMID: 33768781
In COVID-19 patients receiving enoxaparin and antiplatelets therapy, aggregometry and thromboelastography might be considered an adjunctive tool to identify the time to perform procedures at risk of bleeding, such as...
9.
Therapeutic effects of adenosine in high flow 21% oxygen aereosol in patients with Covid19-pneumonia
Correale P, Caracciolo M, Bilotta F, Conte M, Cuzzola M, Falcone C, et al.
PLoS One
. 2020 Oct;
15(10):e0239692.
PMID: 33031409
Background: SARS-Cov2 infection may trigger lung inflammation and acute-respiratory-distress-syndrome (ARDS) that requires active ventilation and may have fatal outcome. Considering the severity of the disease and the lack of active...
10.
Caracciolo M, Macheda S, Labate D, Tescione M, La Scala S, Vadala E, et al.
Front Immunol
. 2020 Sep;
11:1942.
PMID: 32983123
Severe cases of COVID-19 present with serious lung inflammation, acute respiratory distress syndrome and multiorgan damage. SARS-CoV-2 infection is associated with high cytokine levels, including interleukin-6 and certain subsets of...