Sebastian Susperreguy
Overview
Explore the profile of Sebastian Susperreguy including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
183
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0
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Recent Articles
1.
Susperreguy S, Yamashita M, Choi C, Liao Y, Burch L, Blankenship T, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2411389121.
PMID: 39602257
Using genetically engineered mice and cell lines derived from genetically engineered mice we show that depletion of ER delimited Ca stores activates heteromeric Ca entry (SOCE) channels formed obligatorily, but...
2.
Broker-Lai J, Rego Terol J, Richter C, Mathar I, Wirth A, Kopf S, et al.
EMBO J
. 2024 Oct;
43(23):5813-5836.
PMID: 39375537
Hypoglycemia triggers autonomic and endocrine counter-regulatory responses to restore glucose homeostasis, a response that is impaired in patients with diabetes and its long-term complication hypoglycemia-associated autonomic failure (HAAF). We show...
3.
Lin Y, Cui X, Cao Q, Bi R, Liu Y, Jing D, et al.
Int Immunopharmacol
. 2023 Jan;
115:109655.
PMID: 36592529
The transient receptor potential canonical (TRPC) channels, encoded in seven non-allelic genes, are important contributors to calcium fluxes, are strongly associated with various diseases. Here we explored the consequences of...
4.
Formoso K, Susperreguy S, Freichel M, Birnbaumer L
Sci Rep
. 2020 May;
10(1):7227.
PMID: 32350291
The seven-member transient receptor potential canonical genes (TRPC1-7) encode cation channels linked to several human diseases. There is little understanding of the participation of each TRPC in each pathology, considering...
5.
He X, Li S, Liu B, Susperreguy S, Formoso K, Yao J, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(23):E4582-E4591.
PMID: 28526717
The injury phase after myocardial infarcts occurs during reperfusion and is a consequence of calcium release from internal stores combined with calcium entry, leading to cell death by apoptopic and...
6.
Toneatto J, Charo N, Susperreguy S, Piwien-Pilipuk G
Medicina (B Aires)
. 2013 Oct;
73(5):401-5.
PMID: 24152393
Glucocorticoids play an important role in adipogenesis via the glucocorticoid receptor (GR) that forms a heterocomplex with Hsp90-Hsp70 and a high molecular weight immunophilin FKBP51 or FKBP52. We have found...
7.
Toneatto J, Guber S, Charo N, Susperreguy S, Schwartz J, Galigniana M, et al.
J Cell Sci
. 2013 Oct;
126(Pt 23):5357-68.
PMID: 24101724
Glucocorticoids play an important role in adipogenesis through the glucocorticoid receptor (GR) that forms a heterocomplex with Hsp90•Hsp70 and one high molecular weight immunophilin, either FKBP51 or FKBP52. When 3T3-L1...
8.
Montesinos M, Alamino V, Mascanfroni I, Susperreguy S, Gigena N, Masini-Repiso A, et al.
Steroids
. 2011 Nov;
77(1-2):67-76.
PMID: 22056479
Glucocorticoids (GCs) are widely used as anti-inflammatory and immunosuppressive agents. Several studies have indicated the important role of dendritic cells (DCs), highly specialized antigen-presenting and immunomodulatory cells, in GC-mediated suppression...
9.
Susperreguy S, Prendes L, Desbats M, Charo N, Brown K, MacDougald O, et al.
Exp Cell Res
. 2010 Dec;
317(6):706-23.
PMID: 21122806
How the co-ordinated events of gene activation and silencing during cellular differentiation are influenced by spatial organization of the cell nucleus is still poorly understood. Little is known about the...
10.
Susperreguy S, Munoz L, Tkalenko N, Mascanfroni I, Alamino V, Montesinos M, et al.
Clin Endocrinol (Oxf)
. 2010 Nov;
74(3):346-53.
PMID: 21091751
Objective: Idiopathic short stature (ISS) describes short children with normal GH secretion. Although GH treatment increases their heights, growth response to the therapy differs among patients. Thyroid hormones (TH) are...