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Sebastian Stasik

Explore the profile of Sebastian Stasik including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 459
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Recent Articles
1.
Stasik S, Eckardt J, Rollig C, Baldus C, Platzbecker U, Serve H, et al.
Br J Haematol . 2025 Mar; PMID: 40041934
IKZF1 mutations are recurrent alterations in acute myeloid leukaemia (AML), and hotspot point mutation, N159S, has recently been associated with unique gene expression and adverse risk. To better understand the...
2.
Ruhnke L, Bill M, Zukunft S, Eckardt J, Schafer S, Stasik S, et al.
Blood Adv . 2024 Nov; PMID: 39504561
In 2022, the European LeukemiaNet (ELN) risk stratification for patients with AML has been updated. We aimed to validate the prognostic value of the 2022 ELN classification (ELN22) evaluating 1,570...
3.
Eckardt J, Hahn W, Rollig C, Stasik S, Platzbecker U, Muller-Tidow C, et al.
NPJ Digit Med . 2024 Mar; 7(1):76. PMID: 38509224
Clinical research relies on high-quality patient data, however, obtaining big data sets is costly and access to existing data is often hindered by privacy and regulatory concerns. Synthetic data generation...
4.
Georgi J, Stasik S, Kramer M, Meggendorfer M, Rollig C, Haferlach T, et al.
Leukemia . 2024 Jan; 38(2):281-290. PMID: 38228680
Despite recent refinements in the diagnostic and prognostic assessment of CEBPA mutations in AML, several questions remain open, i.e. implications of different types of basic region leucin zipper (bZIP) mutations,...
5.
Eckardt J, Stasik S, Rollig C, Petzold A, Sauer T, Scholl S, et al.
Leukemia . 2023 Oct; 37(12):2395-2403. PMID: 37833543
Genetic lesions of IKZF1 are frequent events and well-established markers of adverse risk in acute lymphoblastic leukemia. However, their function in the pathophysiology and impact on patient outcome in acute...
6.
Eckardt J, Bill M, Rausch C, Metzeler K, Spiekermann K, Stasik S, et al.
Leukemia . 2023 Sep; 37(11):2282-2285. PMID: 37679502
No abstract available.
7.
Mohrmann L, Cuberi A, Bruckmann S, Stasik S, Heukamp L, Bornhauser M, et al.
JCO Precis Oncol . 2023 Jun; 7:e2200666. PMID: 37262393
No abstract available.
8.
Georgi J, Stasik S, Eckardt J, Zukunft S, Hartwig M, Rollig C, et al.
Blood Cancer J . 2023 May; 13(1):88. PMID: 37236968
Tandem-duplication mutations of the UBTF gene (UBTF-TDs) coding for the upstream binding transcription factor have recently been described in pediatric patients with acute myeloid leukemia (AML) and were found to...
9.
Eckardt J, Rollig C, Metzeler K, Heisig P, Stasik S, Georgi J, et al.
Commun Med (Lond) . 2023 May; 3(1):68. PMID: 37198246
Background: Increasingly large and complex biomedical data sets challenge conventional hypothesis-driven analytical approaches, however, data-driven unsupervised learning can detect inherent patterns in such data sets. Methods: While unsupervised analysis in...
10.
Eckardt J, Stasik S, Rollig C, Sauer T, Scholl S, Hochhaus A, et al.
Blood Cancer J . 2023 Jan; 13(1):18. PMID: 36693840
Functional perturbations of the cohesin complex with subsequent changes in chromatin structure and replication are reported in a multitude of cancers including acute myeloid leukemia (AML). Mutations of its STAG2...