Sebastian Schatzle
Overview
Explore the profile of Sebastian Schatzle including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
306
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0
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Recent Articles
1.
Sammut S, Galson J, Minter R, Sun B, Chin S, De Mattos-Arruda L, et al.
Nat Immunol
. 2024 May;
25(5):916-924.
PMID: 38698238
B cells and T cells are important components of the adaptive immune system and mediate anticancer immunity. The T cell landscape in cancer is well characterized, but the contribution of...
2.
Krebs S, Kwon Y, Schramm C, Law W, Donofrio G, Zhou K, et al.
Immunity
. 2019 Mar;
50(3):677-691.e13.
PMID: 30876875
Lineage-based vaccine design is an attractive approach for eliciting broadly neutralizing antibodies (bNAbs) against HIV-1. However, most bNAb lineages studied to date have features indicative of unusual recombination and/or development....
3.
Williams L, Ofek G, Schatzle S, McDaniel J, Lu X, Nicely N, et al.
Sci Immunol
. 2017 Aug;
2(7).
PMID: 28783671
Induction of broadly neutralizing antibodies (bnAbs) is a goal of HIV-1 vaccine development. Antibody 10E8, reactive with the distal portion of the membrane-proximal external region (MPER) of HIV-1 gp41, is...
4.
Increased cathepsin S in Prdm1 dendritic cells alters the T cell repertoire and contributes to lupus
Kim S, Schatzle S, Ahmed S, Haap W, Jang S, Gregersen P, et al.
Nat Immunol
. 2017 Jul;
18(9):1016-1024.
PMID: 28692065
Aberrant population expansion of follicular helper T cells (T cells) occurs in patients with lupus. An unanswered question is whether an altered repertoire of T cell antigen receptors (TCRs) is...
5.
Hohne M, Schatzle S, Jochens H, Robins K, Bornscheuer U
Nat Chem Biol
. 2010 Sep;
6(11):807-13.
PMID: 20871599
Biocatalysis has emerged as a powerful alternative to traditional chemistry, especially for asymmetric synthesis. One key requirement during process development is the discovery of a biocatalyst with an appropriate enantiopreference...
6.
Schatzle S, Hohne M, Robins K, Bornscheuer U
Anal Chem
. 2010 Feb;
82(5):2082-6.
PMID: 20148590
Amine-transaminases (ATAs, omega-transaminases, omega-TA) are PLP-dependent enzymes that catalyze amino group transfer reactions. In contrast to the widespread and well-known amino acid-transaminases, ATAs are able to convert substrates lacking an...
7.
Schatzle S, Hohne M, Redestad E, Robins K, Bornscheuer U
Anal Chem
. 2009 Sep;
81(19):8244-8.
PMID: 19739593
For the biocatalytic preparation of optically active amines, omega-transaminases (omega-TA) are of special interest since they allow the asymmetric synthesis starting from prostereogenic ketones with 100% yield. To facilitate the...
8.
Rzeznicka K, Schatzle S, Bottcher D, Klein J, Bornscheuer U
Appl Microbiol Biotechnol
. 2009 Aug;
85(5):1417-25.
PMID: 19662400
The nitrile hydratase (NHase, EC 4.2.1.84) genes (alpha and beta subunit) and the corresponding activator gene from Rhodococcus equi TG328-2 were cloned and sequenced. This Fe-type NHase consists of 209...