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Sebastian Samer

Explore the profile of Sebastian Samer including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 111
Followers 0
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Recent Articles
1.
Karpova A, Samer S, Turacak R, Yuanxiang P, Kreutz M
Cell Mol Life Sci . 2023 Jul; 80(8):228. PMID: 37491479
Nuclear Ca waves elicited by NMDAR and L-type voltage-gated Ca-channels as well as protein transport from synapse-to-nucleus are both instrumental in control of plasticity-related gene expression. At present it is...
2.
Grochowska K, Gomes G, Raman R, Kaushik R, Sosulina L, Kaneko H, et al.
EMBO J . 2023 Jan; 42(4):e112453. PMID: 36594364
Synaptic dysfunction caused by soluble β-amyloid peptide (Aβ) is a hallmark of early-stage Alzheimer's disease (AD), and is tightly linked to cognitive decline. By yet unknown mechanisms, Aβ suppresses the...
3.
Reyes-Resina I, Samer S, Kreutz M, Oelschlegel A
Front Mol Neurosci . 2021 Dec; 14:767384. PMID: 34867190
The role of sleep for brain function has been in the focus of interest for many years. It is now firmly established that sleep and the corresponding brain activity is...
4.
Samer S, Raman R, Laube G, Kreutz M, Karpova A
Mol Brain . 2021 Jan; 14(1):9. PMID: 33436037
Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to...
5.
Schroder N, Schaffrath A, Welter J, Putzka T, Griep A, Ziegler P, et al.
J Neuroinflammation . 2020 Apr; 17(1):131. PMID: 32331524
Background: An important hallmark of Alzheimer's disease (AD) is the increase of Aβ1-42 burden and its accumulation to senile plaques, leading the reactive gliosis and neurodegeneration. The modulation of glia...
6.
Wassouf Z, Hentrich T, Samer S, Rotermund C, Kahle P, Ehrlich I, et al.
Front Cell Neurosci . 2018 May; 12:112. PMID: 29755323
Onset and progression of neurodegenerative disorders, including synucleinopathies such as Parkinson's disease, have been associated with various environmental factors. A highly compelling association from a therapeutic point of view has...
7.
Weber J, Golla M, Guaitoli G, Wanichawan P, Hayer S, Hauser S, et al.
Brain . 2017 Mar; 140(5):1280-1299. PMID: 28334907
Ataxin-3, the disease protein in Machado-Joseph disease, is known to be proteolytically modified by various enzymes including two major families of proteases, caspases and calpains. This processing results in the...
8.
Kipp M, Wagenknecht N, Beyer C, Samer S, Wuerfel J, Nikoubashman O
Cell Mol Life Sci . 2014 Nov; 72(6):1127-47. PMID: 25417212
There is a broad consensus that MS represents more than an inflammatory disease: it harbors several characteristic aspects of a classical neurodegenerative disorder, i.e. damage to axons, synapses and nerve...