Sebastian R Nielsen
Overview
Explore the profile of Sebastian R Nielsen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
826
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rafaeva M, Jensen A, Horton E, Zornhagen K, Strobech J, Fleischhauer L, et al.
Front Immunol
. 2023 Aug;
14:1154528.
PMID: 37539058
The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and pancreatic cancer. Stromal-derived extracellular matrix (ECM) is significantly altered in desmoplasia,...
2.
Strobech J, Giuriatti P, Stagaard R, De Sepulveda P, Nielsen S, Erler J
Front Oncol
. 2023 Mar;
13:1096499.
PMID: 36969004
Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal 5-year survival rate of less than 10%, predominantly due to delayed diagnosis and a lack of effective treatment options. In the...
3.
Sanchez-Paulete A, Mateus-Tique J, Mollaoglu G, Nielsen S, Marks A, Lakshmi A, et al.
Cancer Immunol Res
. 2022 Sep;
10(11):1354-1369.
PMID: 36095236
Tumor-associated macrophages (TAM) are one of the most abundant cell types in many solid tumors and typically exert protumor effects. This has led to an interest in macrophage-depleting agents for...
4.
Dhainaut M, Rose S, Akturk G, Wroblewska A, Nielsen S, Park E, et al.
Cell
. 2022 Mar;
185(7):1223-1239.e20.
PMID: 35290801
While CRISPR screens are helping uncover genes regulating many cell-intrinsic processes, existing approaches are suboptimal for identifying extracellular gene functions, particularly in the tissue context. Here, we developed an approach...
5.
Rafaeva M, Horton E, Jensen A, Madsen C, Reuten R, Willacy O, et al.
Adv Healthc Mater
. 2021 Nov;
11(1):e2100684.
PMID: 34734500
Metastatic cancer spread is responsible for most cancer-related deaths. To colonize a new organ, invading cells adapt to, and remodel, the local extracellular matrix (ECM), a network of proteins and...
6.
Nielsen S, Strobech J, Horton E, Jackstadt R, Laitala A, Bravo M, et al.
Nat Commun
. 2021 Jun;
12(1):3414.
PMID: 34099731
Pancreatic ductal adenocarcinoma (PDAC) patients have a 5-year survival rate of only 8% largely due to late diagnosis and insufficient therapeutic options. Neutrophils are among the most abundant immune cell...
7.
Quaranta V, Rainer C, Nielsen S, Raymant M, Ahmed M, Engle D, et al.
Cancer Res
. 2018 May;
78(15):4253-4269.
PMID: 29789416
The ability of disseminated cancer cells to evade the immune response is a critical step for efficient metastatic progression. Protection against an immune attack is often provided by the tumor...
8.
Nielsen S, Schmid M
Mediators Inflamm
. 2017 Feb;
2017:9624760.
PMID: 28210073
Macrophages are one of the most abundant immune cells in the tumour microenvironment of solid tumours and their presence correlates with reduced survival in most cancers. Macrophages are present at...
9.
Ireland L, Santos A, Ahmed M, Rainer C, Nielsen S, Quaranta V, et al.
Cancer Res
. 2016 Oct;
76(23):6851-6863.
PMID: 27742686
Tumor-associated macrophages (TAM) and myofibroblasts are key drivers in cancer that are associated with drug resistance in many cancers, including pancreatic ductal adenocarcinoma (PDAC). However, our understanding of the molecular...
10.
Nielsen S, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, et al.
Nat Cell Biol
. 2016 Jun;
18(7):822.
PMID: 27350447
No abstract available.