Sebastian Miles
Overview
Explore the profile of Sebastian Miles including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
29
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Recent Articles
1.
Mourglia-Ettlin G, Gonzalez-Porcile M, Planells-Romeo V, Long-Albin A, Carrillo-Serradell L, Miles S, et al.
J Fungi (Basel)
. 2024 Oct;
10(10).
PMID: 39452619
is included in the World Health Organization fungal priority pathogen list, complied to expedite improved research and public-health interventions. The limited number of available antifungal drugs, their associated toxicity, and...
2.
Garcia-Luna J, Rivero-Osorio F, Gonzalez-Porcile M, Arbildi P, Miles S, Magnone J, et al.
Parasite Immunol
. 2024 Apr;
46(4):e13034.
PMID: 38625016
Scavenger receptors participate in a wide range of biological functions after binding to multiple non-self or altered self-ligands. Among them, CD5 and CD6 are lymphocyte scavenger receptors known to interact...
3.
Miles S, Dematteis S, Mourglia-Ettlin G
Biologicals
. 2023 May;
82:101684.
PMID: 37201271
Vaccines are among the most important advances in medicine throughout the human history. However, conventional vaccines exhibit several drawbacks in terms of design and production costs. Peptide-based vaccines are attractive...
4.
Miles S, Mourglia-Ettlin G, Fernandez V
Mol Biochem Parasitol
. 2023 Apr;
254:111559.
PMID: 37024059
Glutathione transferase enzymes (GSTs) are believed to be a major detoxification system in helminth parasites and have been associated with immunomodulation of the host response. Echinococcus granulosus sensu lato (s.l.)...
5.
Miles S, Mourglia-Ettlin G, Fernandez V
Gene
. 2022 Jun;
835:146659.
PMID: 35680021
Glutathione transferases (GSTs) perform catalytic and non-catalytic activities, mostly involved in stress-response and cell detoxification. Helminth parasites express several GSTs of multiple classes that are involved in the neutralization of...
6.
Miles S, Magnone J, Garcia-Luna J, Dematteis S, Mourglia-Ettlin G
Acta Trop
. 2022 Mar;
230:106410.
PMID: 35300939
Echinococcus granulosus sensu lato (s.l.) is the helminth parasite responsible for cystic echinococcosis, a neglected tropical disease currently affecting millions of people worldwide. Incomplete knowledge on the parasite biochemistry contributes,...
7.
Miles S, Magnone J, Garcia-Luna J, Ancarola M, Cucher M, Dematteis S, et al.
Int J Parasitol
. 2021 Jul;
51(12):989-997.
PMID: 34216624
Cystic echinococcosis is a globally distributed zoonosis caused by cestodes of the Echinococcus granulosus sensu lato (s.l.) complex, with Echinococcus ortleppi mainly involved in cattle infection. Protoscoleces show high developmental...
8.
Garcia-Luna J, Magnone J, Miles S, Lopez-Santurio C, Dematteis S, Mourglia-Ettlin G
Parasite Immunol
. 2020 Oct;
43(3):e12802.
PMID: 33098129
Polyreactive antibodies (pAb) bind to a broad range of unrelated structures, providing hosts with functional components able to rapidly recognize and protect against different pathogens. However, their roles against helminth...
9.
Miles S, Velasco-de-Andres M, Lozano F, Mourglia-Ettlin G
Int J Biol Macromol
. 2020 Sep;
164:3718-3728.
PMID: 32891642
Echinococcus granulosus sensu lato (s.l.) is a cestode parasite affecting both human and livestock health. Recombinant ectodomains of human scavenger receptors CD5 (rshCD5) and CD6 (rshCD6) were previously reported to...
10.
Miles S, Magnone J, Cyrklaff M, Arbildi P, Frischknecht F, Dematteis S, et al.
Immunobiology
. 2020 Feb;
225(3):151916.
PMID: 32107022
Successful establishment of a parasite infection depends partially on the host intrinsic susceptibility to the pathogen. In cystic echinococcosis (CE), a zoonotic disease caused by the cestode parasite Echinococcus granulosus,...