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Sebastian Hiller

Explore the profile of Sebastian Hiller including associated specialties, affiliations and a list of published articles. Areas
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Articles 127
Citations 4602
Followers 0
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Recent Articles
1.
Trager L, Degen M, Pereira J, Durairaj J, Teixeira R, Hiller S, et al.
Nucleic Acids Res . 2025 Mar; 53(5). PMID: 40052821
Protein-primed DNA replication is a unique mechanism, bioorthogonal to other known DNA replication modes. It relies on specialised single-stranded DNA (ssDNA)-binding proteins (SSBs) to stabilise ssDNA intermediates by unknown mechanisms....
2.
Santi I, Teixeira R, Manfredi P, Hernandez Gonzalez H, Spiess D, Mas G, et al.
EMBO J . 2024 Sep; 43(21):5211-5236. PMID: 39322758
Toxin-antitoxin (TA) systems are widespread in bacteria and implicated in genome stability, virulence, phage defense, and persistence. TA systems have diverse activities and cellular targets, but their physiological roles and...
3.
Lewis K, Lee R, Brotz-Oesterhelt H, Hiller S, Rodnina M, Schneider T, et al.
Nature . 2024 Jul; 632(8023):39-49. PMID: 39085542
In this Review, we explore natural product antibiotics that do more than simply inhibit an active site of an essential enzyme. We review these compounds to provide inspiration for the...
4.
Berhanu S, Majumder S, Muntener T, Whitehouse J, Berner C, Bera A, et al.
Science . 2024 Jul; 385(6706):282-288. PMID: 39024453
Transmembrane β-barrels have considerable potential for a broad range of sensing applications. Current engineering approaches for nanopore sensors are limited to naturally occurring channels, which provide suboptimal starting points. By...
5.
Baumgart J, Hiller S, Stroh K, Kloth M, Lang H
Cancers (Basel) . 2024 Feb; 16(3). PMID: 38339321
Background: Treatment of CRLM with major vessel involvement is still challenging and valid data on outcomes are still rare. We analyzed our experience of hepatectomies with resection and reconstruction of...
6.
Berhanu S, Majumder S, Muntener T, Whitehouse J, Berner C, Bera A, et al.
bioRxiv . 2024 Jan; PMID: 38187764
Transmembrane β-barrels (TMBs) are widely used for single molecule DNA and RNA sequencing and have considerable potential for a broad range of sensing and sequencing applications. Current engineering approaches for...
7.
Sollier J, Basler M, Broz P, Dittrich P, Drescher K, Egli A, et al.
Nat Microbiol . 2024 Jan; 9(1):1-3. PMID: 38177300
No abstract available.
8.
Rath P, Hermann A, Schaefer R, Agustoni E, Vonach J, Siegrist M, et al.
Nat Commun . 2023 Sep; 14(1):5648. PMID: 37704632
The outer membrane insertase of Gram-negative bacteria, BAM, is a key target for urgently needed novel antibiotics. Functional reconstitutions of BAM have so far been limited to synthetic membranes and...
9.
Manioglu S, Modaresi S, Thoma J, Overall S, Upert G, Luther A, et al.
Nat Commun . 2023 Aug; 14(1):4773. PMID: 37558675
No abstract available.
10.
Manner C, Teixeira R, Saha D, Kaczmarczyk A, Zemp R, Wyss F, et al.
Nat Microbiol . 2023 Jun; 8(8):1520-1533. PMID: 37291227
Efficient colonization of mucosal surfaces is essential for opportunistic pathogens like Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize adherence, virulence and dispersal is largely unclear. Here...