Sebastian Fantini
Overview
Explore the profile of Sebastian Fantini including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
195
Followers
0
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Recent Articles
1.
Bianchi E, Rontauroli S, Tavernari L, Mirabile M, Pedrazzi F, Genovese E, et al.
Leukemia
. 2023 Mar;
37(5):1068-1079.
PMID: 36928007
Clonal myeloproliferation and development of bone marrow (BM) fibrosis are the major pathogenetic events in myelofibrosis (MF). The identification of novel antifibrotic strategies is of utmost importance since the effectiveness...
2.
Genovese E, Mirabile M, Rontauroli S, Sartini S, Fantini S, Tavernari L, et al.
Antioxidants (Basel)
. 2022 Jan;
11(1).
PMID: 35052617
Myelofibrosis (MF) is the Philadelphia-negative myeloproliferative neoplasm characterized by the worst prognosis and no response to conventional therapy. Driver mutations in and impact on JAK-STAT pathway activation but also on...
3.
Increased Plasma Levels of lncRNAs , and Correlate with Negative Prognostic Factors in Myelofibrosis
Fantini S, Rontauroli S, Sartini S, Mirabile M, Bianchi E, Badii F, et al.
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638230
Long non-coding RNAs (lncRNAs) have been recently described as key mediators in the development of hematological malignancies. In the last years, circulating lncRNAs have been proposed as a new class...
4.
Rontauroli S, Castellano S, Guglielmelli P, Zini R, Bianchi E, Genovese E, et al.
Blood Adv
. 2021 Mar;
5(5):1452-1462.
PMID: 33666652
Myelofibrosis (MF) belongs to the family of classic Philadelphia-negative myeloproliferative neoplasms (MPNs). It can be primary myelofibrosis (PMF) or secondary myelofibrosis (SMF) evolving from polycythemia vera (PV) or essential thrombocythemia...
5.
Bertesi M, Fantini S, Alecci C, Lotti R, Martello A, Parenti S, et al.
Front Med (Lausanne)
. 2021 Feb;
7:579383.
PMID: 33585499
The mRNA-destabilizing protein tristetraprolin (TTP), encoded by the gene, is known to be able to end inflammatory responses by directly targeting and destabilizing mRNAs encoding pro-inflammatory cytokines. We analyzed its...
6.
Parenti S, Rontauroli S, Carretta C, Mallia S, Genovese E, Chiereghin C, et al.
NPJ Precis Oncol
. 2021 Feb;
5(1):4.
PMID: 33542466
Disease progression of myeloproliferative neoplasms is the result of increased genomic complexity. Since the ability to predict disease evolution is crucial for clinical decisions, we studied single-cell genomics and transcriptomics...
7.
Carretta C, Mallia S, Genovese E, Parenti S, Rontauroli S, Bianchi E, et al.
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33036143
Single-cell genomics has become the method of choice for the study of heterogeneous cell populations and represents an elective application in defining the architecture and clonal evolution in hematological neoplasms....
8.
Zanfi E, Fantini S, Lotti R, Bertesi M, Marconi A, Grande A, et al.
Int J Mol Sci
. 2020 Aug;
21(16).
PMID: 32784485
The Wnt/CTNNB1 pathway is often deregulated in epithelial tumors. The gene, encoding the mRNA binding protein Tristetraprolin (TTP), is downregulated in several cancers, where it has been described to behave...
9.
Lauriola A, Martello A, Fantini S, Marverti G, Zanocco-Marani T, Davalli P, et al.
Cancers (Basel)
. 2020 Apr;
12(4).
PMID: 32316593
Mitotic perturbations frequently lead to chromosome mis-segregation that generates genome instability, thereby triggering tumor onset and/or progression. Error-free mitosis depends on fidelity-monitoring systems that ensure the temporal and spatial coordination...
10.
Mammoli F, Parenti S, Lomiento M, Gemelli C, Atene C, Grande A, et al.
Exp Cell Res
. 2019 Jun;
382(1):111445.
PMID: 31152707
MicroRNAs (miRNA) are small noncoding RNAs that regulate gene expression by targeting mRNAs in a sequence specific manner, thereby determining their degradation or inhibiting translation. They are involved in processes...