Sebastian Attig
Overview
Explore the profile of Sebastian Attig including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
2788
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0
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Recent Articles
1.
Ziegler N, Cortes-Lopez M, Alt F, Sprang M, Ustjanzew A, Lehmann N, et al.
Oncoimmunology
. 2023 Mar;
12(1):2184143.
PMID: 36875548
Despite massive improvements in the treatment of B-ALL through CART-19 immunotherapy, a large number of patients suffer a relapse due to loss of the targeted epitope. Mutations in the locus...
2.
Formes H, Bernardes J, Mann A, Bayer F, Pontarollo G, Kiouptsi K, et al.
iScience
. 2021 Oct;
24(10):103092.
PMID: 34622147
The gut microbiota affects remote organ functions but its impact on organotypic endothelial cell (EC) transcriptomes remains unexplored. The liver endothelium encounters microbiota-derived signals and metabolites via the portal circulation....
3.
Price L, Adamow M, Attig S, Fecci P, Norberg P, Reap E, et al.
Cytometry A
. 2020 Oct;
99(1):107-116.
PMID: 33090656
Results from the first gating proficiency panel of intracellular cytokine staining (ICS) highlighted the value of using a consensus gating approach to reduce the variability across laboratories in reported %CD8...
4.
Sahin U, Oehm P, Derhovanessian E, Jabulowsky R, Vormehr M, Gold M, et al.
Nature
. 2020 Jul;
585(7823):107-112.
PMID: 32728218
Treating patients who have cancer with vaccines that stimulate a targeted immune response is conceptually appealing, but cancer vaccine trials have not been successful in late-stage patients with treatment-refractory tumours....
5.
Sahin U, Derhovanessian E, Miller M, Kloke B, Simon P, Lower M, et al.
Nature
. 2017 Jul;
547(7662):222-226.
PMID: 28678784
T cells directed against mutant neo-epitopes drive cancer immunity. However, spontaneous immune recognition of mutations is inefficient. We recently introduced the concept of individualized mutanome vaccines and implemented an RNA-based...
6.
Fischer J, Paret C, El Malki K, Alt F, Wingerter A, Neu M, et al.
J Immunother
. 2017 Apr;
40(5):187-195.
PMID: 28441264
B-cell acute lymphoblastic leukemia (B-ALL) is the commonest childhood cancer and the prognosis of children with relapsed or therapy refractory disease remains a challenge. Treatment with chimeric antigen receptor-modified T...
7.
Kranz L, Diken M, Haas H, Kreiter S, Loquai C, Reuter K, et al.
Nature
. 2016 Jun;
534(7607):396-401.
PMID: 27281205
Lymphoid organs, in which antigen presenting cells (APCs) are in close proximity to T cells, are the ideal microenvironment for efficient priming and amplification of T-cell responses. However, the systemic...
8.
Bidmon N, Attig S, Rae R, Schroder H, Omokoko T, Simon P, et al.
J Immunol
. 2015 May;
194(12):6177-89.
PMID: 25957167
The systematic assessment of the human immune system bears huge potential to guide rational development of novel immunotherapies and clinical decision making. Multiple assays to monitor the quantity, phenotype, and...
9.
Gouttefangeas C, Chan C, Attig S, Kollgaard T, Rammensee H, Stevanovic S, et al.
Cancer Immunol Immunother
. 2015 Apr;
64(5):585-98.
PMID: 25854580
Multiparameter flow cytometry is an indispensable method for assessing antigen-specific T cells in basic research and cancer immunotherapy. Proficiency panels have shown that cell sample processing, test protocols and data...
10.
Simon P, Omokoko T, Breitkreuz A, Hebich L, Kreiter S, Attig S, et al.
Cancer Immunol Res
. 2014 Sep;
2(12):1230-44.
PMID: 25245536
The determination of the epitope specificity of disease-associated T-cell responses is relevant for the development of biomarkers and targeted immunotherapies against cancer, autoimmune, and infectious diseases. The lack of known...