Sean W Cain
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Explore the profile of Sean W Cain including associated specialties, affiliations and a list of published articles.
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77
Citations
1841
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Recent Articles
1.
Burge M, Lumapas R, Lander A, Thomas B, Phillips A, Cain S
Sleep
. 2025 Feb;
PMID: 39994882
Darkness is equated with sadness. This study explored how light that differentially impacts non-visual photoreception (blue-enriched vs blue-depleted light) affects how we feel about ourselves. In a repeated-measured design, thirty-five...
2.
Windred D, Burns A, Lane J, Olivier P, Rutter M, Saxena R, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(43):e2405924121.
PMID: 39405349
Light enhances or disrupts circadian rhythms, depending on the timing of exposure. Circadian disruption contributes to poor health outcomes that increase mortality risk. Whether personal light exposure predicts mortality risk...
3.
Burns A, Zellers S, Windred D, Daghlas I, Sinnott-Armstrong N, Rutter M, et al.
medRxiv
. 2024 Sep;
PMID: 39314956
Evening chronotypes (a.k.a. "night-owls") are held to be at greater risk for psychiatric disorders. This is postulated to be due to delayed circadian timing increasing the likelihood of circadian misalignment...
4.
Lander A, Phillips A, McGlashan E, Cain S
Front Psychol
. 2024 Aug;
15:1352320.
PMID: 39205984
Exposure to bright light can be visually aversive. This study explored the association between light aversion and various facets of impulsivity. A total of 1,245 participants completed the UPPS-Impulsive Behavior...
5.
Windred D, Burns A, Rutter M, Ching Yeung C, Lane J, Xiao Q, et al.
Lancet Reg Health Eur
. 2024 Jul;
42:100943.
PMID: 39070751
Background: Light at night disrupts circadian rhythms, and circadian disruption is a risk factor for type 2 diabetes. Whether personal light exposure predicts diabetes risk has not been demonstrated in...
6.
Vidafar P, McGlashan E, Burns A, Anderson C, Shechter A, Lockley S, et al.
J Pineal Res
. 2024 Jul;
76(2):e12936.
PMID: 39041348
Women typically sleep and wake earlier than men and have been shown to have earlier circadian timing relative to the light/dark cycle that synchronizes the clock. A potential mechanism for...
7.
Windred D, Anderson C, Jeppe K, Ftouni S, Grant L, Nijagal B, et al.
Sci Rep
. 2024 Jul;
14(1):16796.
PMID: 39039133
Robust circadian rhythms are essential for optimal health. The central circadian clock controls temperature rhythms, which are known to organize the timing of peripheral circadian rhythms in rodents. In humans,...
8.
Spitschan M, Vidafar P, Cain S, Phillips A, Lambert B
Clocks Sleep
. 2024 Mar;
6(1):114-128.
PMID: 38534797
In humans, the nocturnal secretion of melatonin by the pineal gland is suppressed by ocular exposure to light. In the laboratory, melatonin suppression is a biomarker for this neuroendocrine pathway....
9.
Goodman M, Dashti H, Lane J, Windred D, Burns A, Jones S, et al.
J Am Heart Assoc
. 2023 Dec;
12(24):e030568.
PMID: 38084713
Background: Excessive daytime sleepiness (EDS), experienced in 10% to 20% of the population, has been associated with cardiovascular disease and death. However, the condition is heterogeneous and is prevalent in...
10.
Chang A, Anderson C, Cain S, Reichenberger D, Ronda J, Lockley S, et al.
Sleep Health
. 2023 Nov;
10(1S):S67-S75.
PMID: 37989626
Objectives: For optimal health and well-being the sleep episode and the circadian timing system should be properly aligned. We evaluated the effectiveness of different dynamic light and sleep/wake shift schedules...