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Sean Tanabe

Explore the profile of Sean Tanabe including associated specialties, affiliations and a list of published articles. Areas
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Citations 222
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Recent Articles
1.
Wehrman J, Schuller P, Casey C, Scheinin A, Kallionpaa R, Valli K, et al.
Br J Anaesth . 2024 Dec; 134(3):727-735. PMID: 39665912
Background: The ability of current depth-of-anaesthesia monitors to differentiate subtle changes in the conscious state has not been well characterised. We examine the variability in bispectral index (BIS) scores associated...
2.
Han J, Xie Q, Wu X, Huang Z, Tanabe S, Fogel S, et al.
Cell Rep . 2023 Dec; 43(1):113633. PMID: 38159279
Arousal and awareness are two components of consciousness whose neural mechanisms remain unclear. Spontaneous peaks of global (brain-wide) blood-oxygenation-level-dependent (BOLD) signal have been found to be sensitive to changes in...
3.
Casey C, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al.
Br J Anaesth . 2023 Nov; 132(2):300-311. PMID: 37914581
Background: Understanding the neural correlates of consciousness has important ramifications for the theoretical understanding of consciousness and for clinical anaesthesia. A major limitation of prior studies is the use of...
4.
Wehrman J, Casey C, Tanabe S, Mohanta S, Filbey W, Weber L, et al.
Br J Anaesth . 2023 Aug; 131(4):705-714. PMID: 37541951
Background: Sensory disconnection is a key feature of sleep and anaesthesia. We have proposed that predictive coding offers a framework for understanding the mechanisms of disconnection. Low doses of ketamine...
5.
Tanabe S, Lee H, Wang S, Hudetz A
Neuroscience . 2023 Jul; 528:54-63. PMID: 37473851
Recurring spike sequences are thought to underlie cortical computations and may be essential for information processing in the conscious state. How anesthesia at graded levels may influence spontaneous and stimulus-related...
6.
Gjini K, Casey C, Tanabe S, Bo A, Parker M, White M, et al.
Brain Commun . 2022 Oct; 4(5):fcac209. PMID: 36226138
Altered predictive coding may underlie the reduced auditory mismatch negativity amplitude observed in patients with dementia. We hypothesized that accumulating dementia-associated pathologies, including amyloid and tau, lead to disturbed predictions...
7.
Casey C, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al.
Neuroimage . 2022 Oct; 263:119657. PMID: 36209793
The neural mechanisms through which individuals lose sensory awareness of their environment during anesthesia remains poorly understood despite being of vital importance to the field. Prior research has not distinguished...
8.
Tanabe S, Parker M, Lennertz R, Pearce R, Banks M, Sanders R
J Gerontol A Biol Sci Med Sci . 2022 Aug; 77(11):2221-2222. PMID: 35943896
No abstract available.
9.
Casey C, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al.
Br J Anaesth . 2022 Feb; 128(6):1006-1018. PMID: 35148892
Background: How conscious experience becomes disconnected from the environment, or disappears, across arousal states is unknown. We sought to identify the neural correlates of sensory disconnection and unconsciousness using a...
10.
Taylor J, Parker M, Casey C, Tanabe S, Kunkel D, Rivera C, et al.
Br J Anaesth . 2022 Feb; 129(2):219-230. PMID: 35144802
Background: Case-control studies have associated delirium with blood-brain barrier (BBB) permeability. However, this approach cannot determine whether delirium is attributable to high pre-existing permeability or to perioperative changes. We tested...