Sean T May
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Explore the profile of Sean T May including associated specialties, affiliations and a list of published articles.
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36
Citations
732
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Recent Articles
1.
Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature
Wood J, Smith S, Castellanos-Uribe M, Lourdusamy A, May S, Barrett D, et al.
Heliyon
. 2025 Jan;
11(1):e41309.
PMID: 39816516
Isocitrate dehydrogenase wild-type glioblastoma (GBM) is characterised by a heterogeneous genetic landscape resulting from dynamic competition between tumour subclones to survive selective pressures. Improvements in metabolite identification and metabolome coverage...
2.
Nagappan J, Ooi S, Chan K, Kadri F, Nurazah Z, Halim M, et al.
Mol Biol Rep
. 2024 Jan;
51(1):212.
PMID: 38273212
Background: Ganoderma boninense is a phytopathogen of oil palm, causing basal and upper stem rot diseases. Methods: The genome sequence was used as a reference to study gene expression during...
3.
Kumar U, Castellanos-Uribe M, May S, Yague E
Gene
. 2022 Oct;
850:146930.
PMID: 36195266
Resistance to cancer therapeutics represents a leading cause of mortality and is particularly important in cancers, such as triple negative breast cancer, for which no targeted therapy is available, as...
4.
AlMousa L, Salter A, Castellanos M, May S, Langley-Evans S
Nutrients
. 2022 Sep;
14(17).
PMID: 36079843
Vascular endothelial cells have a critical role in the maintenance of cardiovascular function. Evidence suggests that endothelial function may be compromised under conditions of magnesium deficiency, which increases vulnerability to...
5.
Morgan H, Furse S, Dias I, Shabir K, Castellanos M, Khan I, et al.
Commun Biol
. 2022 Sep;
5(1):929.
PMID: 36075960
The underlying mechanisms driving paternally-programmed metabolic disease in offspring remain poorly defined. We fed male C57BL/6 mice either a control normal protein diet (NPD; 18% protein) or an isocaloric low...
6.
Wood J, Abdelrazig S, Evseev S, Ortori C, Castellanos-Uribe M, May S, et al.
Cancers (Basel)
. 2022 Aug;
14(16).
PMID: 36010867
Poor outcomes associated with diffuse high-grade gliomas occur in both adults and children, despite substantial progress made in the molecular characterisation of the disease. Targeting the metabolic requirements of cancer...
7.
Nath M, Romaine S, Koekemoer A, Hamby S, Webb T, Nelson C, et al.
Eur J Heart Fail
. 2022 May;
24(6):1009-1019.
PMID: 35570197
Aims: Chronic heart failure (CHF) is a systemic syndrome with a poor prognosis and a need for novel therapies. We investigated whether whole blood transcriptomic profiling can provide new mechanistic...
8.
Rusu A, Cornhill Z, Canales Coutino B, Uribe M, Lourdusamy A, Markus Z, et al.
Open Biol
. 2021 Sep;
11(9):210077.
PMID: 34493070
Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1...
9.
Kumar U, Hu Y, Masrour N, Castellanos-Uribe M, Harrod A, May S, et al.
Biochem Pharmacol
. 2021 Jul;
192:114692.
PMID: 34298004
Triple-negative metaplastic breast carcinoma (MBC) poses a significant treatment challenge due to lack of targeted therapies and chemotherapy resistance. We isolated a novel MBC cell line, BAS, which showed a...
10.
Babaei-Jadidi R, Dongre A, Miller S, Uribe M, Stewart I, Thompson Z, et al.
Am J Respir Crit Care Med
. 2021 Apr;
204(4):431-444.
PMID: 33882264
Lymphangioleiomyomatosis (LAM) is a multisystem disease that causes lung cysts and respiratory failure. Loss of TSC (tuberous sclerosis complex) gene function results in a clone of "LAM cells" with dysregulated...