Sean P Woodworth
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Explore the profile of Sean P Woodworth including associated specialties, affiliations and a list of published articles.
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9
Citations
132
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Recent Articles
1.
Ling C, Clarke R, Rosetto G, Xu S, Cywar R, Kim D, et al.
ACS Sustain Chem Eng
. 2025 Mar;
13(9):3817-3829.
PMID: 40083642
Polyhydroxyalkanoates (PHAs) are versatile, biobased polyesters that are often targeted for use as degradable thermoplastic replacements for polyolefins. Given the substantial chemical diversity of PHA, their potential as cross-linked polymers...
2.
Kuatsjah E, Schwartz A, Zahn M, Tornesakis K, Kellermyer Z, Ingraham M, et al.
Cell Rep
. 2024 Nov;
43(12):115002.
PMID: 39589922
White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However, their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as carbon sources has only been described recently....
3.
Ruhl I, Nelson R, Katahira R, Kruger J, Chen X, Haugen S, et al.
Microb Biotechnol
. 2024 Sep;
17(9):e70006.
PMID: 39235453
Feedstock variability represents a challenge in lignocellulosic biorefineries, as it can influence both lignocellulose deconstruction and microbial conversion processes for biofuels and biochemicals production. The impact of feedstock variability on...
4.
Gu N, Palumbo C, Bleem A, Sullivan K, Haugen S, Woodworth S, et al.
ACS Cent Sci
. 2024 Jan;
9(12):2277-2285.
PMID: 38161372
Selective lignin depolymerization is a key step in lignin valorization to value-added products, and there are multiple catalytic methods to cleave labile aryl-ether bonds in lignin. However, the overall aromatic...
5.
Cywar R, Ling C, Clarke R, Kim D, Kneucker C, Salvachua D, et al.
Sci Adv
. 2023 Nov;
9(47):eadi1735.
PMID: 37992173
Cross-linked elastomers are stretchable materials that typically are not recyclable or biodegradable. Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are soft and ductile, making these bio-based polymers good candidates for biodegradable elastomers. Elasticity is...
6.
Calvey C, Sanchez I Nogue V, White A, Kneucker C, Woodworth S, Alt H, et al.
Metab Eng
. 2022 Nov;
75:78-90.
PMID: 36368470
Conversion of CO to value-added products presents an opportunity to reduce GHG emissions while generating revenue. Formate, which can be generated by the electrochemical reduction of CO, has been proposed...
7.
Sullivan K, Werner A, Ramirez K, Ellis L, Bussard J, Black B, et al.
Science
. 2022 Oct;
378(6616):207-211.
PMID: 36227984
Mixed plastics waste represents an abundant and largely untapped feedstock for the production of valuable products. The chemical diversity and complexity of these materials, however, present major barriers to realizing...
8.
Ling C, Peabody G, Salvachua D, Kim Y, Kneucker C, Calvey C, et al.
Nat Commun
. 2022 Aug;
13(1):4925.
PMID: 35995792
Muconic acid is a bioprivileged molecule that can be converted into direct replacement chemicals for incumbent petrochemicals and performance-advantaged bioproducts. In this study, Pseudomonas putida KT2440 is engineered to convert...
9.
Kuatsjah E, Johnson C, Salvachua D, Werner A, Zahn M, Szostkiewicz C, et al.
Metab Eng
. 2022 Jan;
70:31-42.
PMID: 34982998
The transformation of 4-hydroxybenzoate (4-HBA) to protocatechuate (PCA) is catalyzed by flavoprotein oxygenases known as para-hydroxybenzoate-3-hydroxylases (PHBHs). In Pseudomonas putida KT2440 (P. putida) strains engineered to convert lignin-related aromatic compounds...
10.
Notonier S, Werner A, Kuatsjah E, Dumalo L, Abraham P, Hatmaker E, et al.
Metab Eng
. 2021 Mar;
65:111-122.
PMID: 33741529
Valorization of lignin, an abundant component of plant cell walls, is critical to enabling the lignocellulosic bioeconomy. Biological funneling using microbial biocatalysts has emerged as an attractive approach to convert...