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Sean M Gibbons

Explore the profile of Sean M Gibbons including associated specialties, affiliations and a list of published articles. Areas
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Articles 92
Citations 13027
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Recent Articles
1.
Diener C, Holscher H, Filek K, Corbin K, Moissl-Eichinger C, Gibbons S
Nat Metab . 2025 Feb; PMID: 39966520
Dietary intake is tightly coupled to gut microbiota composition, human metabolism and the incidence of virtually all major chronic diseases. Dietary and nutrient intake are usually assessed using self-reporting methods,...
2.
Tang G, Carr A, Perez C, Sarmiento K, Levy L, Lampe J, et al.
bioRxiv . 2025 Jan; PMID: 39829744
Absolute bacterial biomass estimation in the human gut is crucial for understanding microbiome dynamics and host-microbe interactions. Current methods for quantifying bacterial biomass in stool, such as flow cytometry, qPCR,...
3.
Qian Y, Menon S, Quinn-Bohmann N, Gibbons S, Venturelli O
bioRxiv . 2025 Jan; PMID: 39803481
Microbial communities play a central role in transforming environments across Earth, driving both physical and chemical changes. By harnessing these capabilities, synthetic microbial communities, assembled from the bottom up, offer...
4.
Byrne A, Diener C, Brown B, Maust B, Feng C, Alinde B, et al.
Microbiome . 2024 Dec; 12(1):261. PMID: 39707483
Background: Infants exposed to HIV but uninfected have altered immune profiles which include heightened systemic inflammation. The mechanism(s) underlying this phenomenon is unknown. Here, we investigated differences in neonatal gut...
5.
Ellis D, Watanabe K, Wilmanski T, Lustgarten M, Ardisson Korat A, Glusman G, et al.
bioRxiv . 2024 Nov; PMID: 39605362
Apolipoprotein E ( ) modifies human aging; specifically, the ε2 and ε4 alleles are among the strongest genetic predictors of longevity and Alzheimer's disease (AD) risk, respectively. However, detailed mechanisms...
6.
Jiang B, Quinn-Bohmann N, Diener C, Nathan V, Han-Hallett Y, Reddivari L, et al.
bioRxiv . 2024 Nov; PMID: 39484551
The colon epithelium plays a key role in the host-microbiome interactions, allowing uptake of various nutrients and driving important metabolic processes. To unravel detailed metabolic activities in the human colon...
7.
Sulaiman J, Thompson J, Qian Y, Vivas E, Diener C, Gibbons S, et al.
Nat Commun . 2024 Aug; 15(1):7416. PMID: 39198411
The human gut pathogen Clostridioides difficile displays substantial inter-strain genetic variability and confronts a changeable nutrient landscape in the gut. We examined how human gut microbiota inter-species interactions influence the...
8.
Valenzuela J, Immanuel S, Wilson J, Turkarslan S, Ruiz M, Gibbons S, et al.
Nat Commun . 2024 Aug; 15(1):7451. PMID: 39198408
Resource partitioning is central to the incredible productivity of microbial communities, including gigatons in annual methane emissions through syntrophic interactions. Previous work revealed how a sulfate reducer (Desulfovibrio vulgaris, Dv)...
9.
Johnson-Martinez J, Diener C, Levine A, Wilmanski T, Suskind D, Ralevski A, et al.
Cell Rep Med . 2024 Jul; 5(7):101646. PMID: 39019013
Bowel movement frequency (BMF) directly impacts the gut microbiota and is linked to diseases like chronic kidney disease or dementia. In particular, prior work has shown that constipation is associated...
10.
Kane A, Chellappa K, Schultz M, Arnold M, Li J, Amorim J, et al.
bioRxiv . 2024 Jul; PMID: 38979132
Nicotinamide adenine dinucleotide (NAD) is essential for many enzymatic reactions, including those involved in energy metabolism, DNA repair and the activity of sirtuins, a family of defensive deacylases. During aging,...