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Scott Snapper

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Articles 41
Citations 1864
Followers 0
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Recent Articles
1.
de Vries M, de Vries M, Meddens C, Meddens C, Hijma H, Hijma H, et al.
bioRxiv . 2025 Feb; PMID: 39975165
Intestinal epithelial cells (IECs) are capable of mounting an adequate antimicrobial inflammatory response to pathogens while tolerating commensals. The underlying regulatory mechanisms of immune sensitivity remain incompletely understood, particularly in...
2.
Lee S, Bushra M, Qiu L, Shao J, Olivera P, Leibovitzh H, et al.
Gastroenterology . 2024 Oct; 168(2):385-388.e3. PMID: 39384162
No abstract available.
3.
Yeh P, Nash K, Charlesworth J, Collen L, Snapper S, Uhlig H
J Pediatr Gastroenterol Nutr . 2024 Feb; 78(4):759-762. PMID: 38356297
No abstract available.
4.
Geem D, Hercules D, Pelia R, Venkateswaran S, Griffiths A, Noe J, et al.
Clin Gastroenterol Hepatol . 2023 Oct; 22(2):368-376.e4. PMID: 37802268
Background & Aims: The evolution of complicated pediatric Crohn's disease (CD) in the era of anti-tumor necrosis factor (aTNF) therapy continues to be described. Because CD progresses from inflammatory to...
5.
Chandrasekaran P, Han Y, Zerbe C, Heller T, DeRavin S, Kreuzberg S, et al.
J Allergy Clin Immunol . 2023 Sep; 152(6):1619-1633.e11. PMID: 37659505
Background: Chronic granulomatous disease (CGD) is caused by defects in any 1 of the 6 subunits forming the nicotinamide adenine dinucleotide phosphate oxidase complex 2 (NOX2), leading to severely reduced...
6.
Wu Y, Gettler K, Kars M, Giri M, Li D, Sevim Bayrak C, et al.
Nat Commun . 2023 Apr; 14(1):2256. PMID: 37080976
Inflammatory bowel disease (IBD) is a group of chronic digestive tract inflammatory conditions whose genetic etiology is still poorly understood. The incidence of IBD is particularly high among Ashkenazi Jews....
7.
Chen B, Collen L, Mowat C, Isaacs K, Singh S, Kane S, et al.
Am J Med . 2022 Sep; 135(12):1453-1460. PMID: 36058305
Background: Emerging data showed patients with chronic inflammatory disorders, including inflammatory bowel disease, are more likely to develop atherosclerotic cardiovascular diseases, heart failure, and atrial fibrillation. This article aims to...
8.
Kerur B, Fiedler K, Stahl M, Hyams J, Stephens M, Lu Y, et al.
J Pediatr Gastroenterol Nutr . 2022 May; 75(1):64-69. PMID: 35622080
Background: Research on the utilization and effectiveness of antitumor necrosis factor (TNF) biologics in children with very early onset inflammatory bowel disease (VEOIBD) is urgently needed. Here we describe anti-TNF...
9.
Dannheim K, Ouahed J, Field M, Snapper S, Raphael B, Glover S, et al.
Am J Surg Pathol . 2022 Jan; 46(6):846-853. PMID: 34985046
Mutations in the tetratricopeptide repeat domain 7A (TTC7A) gene are a rare cause of congenital enteropathy that can result in significant morbidity. TTC7A deficiency leads to disruption of the intestinal...
10.
Bolton C, Smillie C, Pandey S, Elmentaite R, Wei G, Argmann C, et al.
Gastroenterology . 2021 Nov; 162(3):859-876. PMID: 34780721
Background & Aims: Monogenic forms of inflammatory bowel disease (IBD) illustrate the essential roles of individual genes in pathways and networks safeguarding immune tolerance and gut homeostasis. Methods: To build...