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Scott Simonovich

Explore the profile of Scott Simonovich including associated specialties, affiliations and a list of published articles. Areas
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Citations 37
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Recent Articles
1.
Mackman R, Hui H, Perron M, Murakami E, Palmiotti C, Lee G, et al.
J Med Chem . 2021 Apr; 64(8):5001-5017. PMID: 33835812
A discovery program targeting respiratory syncytial virus (RSV) identified -nucleoside (RSV A2 EC = 530 nM) as a phenotypic screening lead targeting the RSV RNA-dependent RNA polymerase (RdRp). Prodrug exploration...
2.
Rescourio G, Gonzalez A, Jabri S, Belmontes B, Moody G, Whittington D, et al.
J Med Chem . 2019 Nov; 62(22):10258-10271. PMID: 31736296
Overexpression of the antiapoptotic protein Mcl-1 provides a survival advantage to some cancer cells, making inhibition of this protein an attractive therapeutic target for the treatment of certain types of...