Scott R Wheeler
Overview
Explore the profile of Scott R Wheeler including associated specialties, affiliations and a list of published articles.
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14
Citations
348
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Recent Articles
1.
Mukherjee S, Sathanoori M, Ma Z, Andreatta M, Lennon P, Wheeler S, et al.
Cancer Genet
. 2017 Oct;
216-217:128-141.
PMID: 29025587
Comprehensive genetic profiling is increasingly important for the clinical workup of hematologic tumors, as specific alterations are now linked to diagnostic characterization, prognostic stratification and therapy selection. To characterize relevant...
2.
Wheeler S, Shi C, Holt J, Vnencak-Jones C
J Gastrointest Oncol
. 2016 Jun;
7(3):E64-71.
PMID: 27284491
Patients with Lynch syndrome often present with multiple synchronous or metachronous colorectal cancers (CRCs). The presence of multiple CRCs with distinct genetic profiles and driver mutations could complicate treatment as...
3.
Wheeler S, Pearson J, Crews S
Dev Biol
. 2011 Nov;
361(2):232-44.
PMID: 22061481
The Drosophila CNS midline glia (MG) are multifunctional cells that ensheath and provide trophic support to commissural axons, and direct embryonic development by employing a variety of signaling molecules. These...
4.
Watson J, Wheeler S, Stagg S, Crews S
Development
. 2011 Feb;
138(7):1285-95.
PMID: 21350018
The Drosophila CNS contains a variety of glia, including highly specialized glia that reside at the CNS midline and functionally resemble the midline floor plate glia of the vertebrate spinal...
5.
Wheeler S, Stagg S, Crews S
BMC Dev Biol
. 2009 Nov;
9:56.
PMID: 19903351
Background: The Drosophila CNS midline cells are an excellent model system to study neuronal and glial development because of their diversity of cell types and the relative ease in identifying...
6.
Wheeler S, Banerjee S, Blauth K, Rogers S, Bhat M, Crews S
Development
. 2009 Mar;
136(7):1147-57.
PMID: 19270173
Glia play crucial roles in ensheathing axons, a process that requires an intricate series of glia-neuron interactions. The membrane-anchored protein Wrapper is present in Drosophila midline glia and is required...
7.
Wheeler S, Stagg S, Crews S
Development
. 2008 Aug;
135(18):3071-9.
PMID: 18701546
The study of how transcriptional control and cell signaling influence neurons and glia to acquire their differentiated properties is fundamental to understanding CNS development and function. The Drosophila CNS midline...
8.
Zhao G, Wheeler S, Skeath J
Int J Dev Biol
. 2007 Feb;
51(2):107-15.
PMID: 17294361
The Drosophila embryonic Central Nervous System (CNS) develops from the ventrolateral region of the embryo, the neuroectoderm. Neuroblasts arise from the neuroectoderm and acquire unique fates based on the positions...
9.
Wheeler S, Kearney J, Guardiola A, Crews S
Dev Biol
. 2006 Apr;
294(2):509-24.
PMID: 16631157
Understanding the generation of neuronal and glial diversity is one of the major goals of developmental neuroscience. The Drosophila CNS midline cells constitute a simple neurogenomic system to study neurogenesis,...
10.
Wheeler S, Skeath J
Gene Expr Patterns
. 2005 Jun;
5(5):695-700.
PMID: 15939382
The achaete-scute (ac/sc) genes are a highly conserved family of transcription factors that play important roles in the development of neural cells in both vertebrates and invertebrates. As such, the...