Scott P Souza
Overview
Explore the profile of Scott P Souza including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
14
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Recent Articles
1.
Alvarez J, Gas-Pascual E, Malhi S, Sanchez-Arcila J, Njume F, van der Wel H, et al.
mBio
. 2024 Sep;
15(10):e0052724.
PMID: 39302131
Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, , is a widespread intracellular parasite of warm-blooded animals whose plasma membrane is covered with GPI-anchored...
2.
Kongsomboonvech A, Garcia-Lopez L, Njume F, Rodriguez F, Souza S, Rosenberg A, et al.
Front Cell Infect Microbiol
. 2023 Jun;
13:1130965.
PMID: 37287466
Introduction: induces a strong CD8 T cell response characterized by the secretion of IFNγ that promotes host survival during infection. The initiation of CD8 T cell IFNγ responses differs widely...
3.
Souza S, Splitt S, Sanchez-Arcila J, Alvarez J, Wilson J, Wizzard S, et al.
PLoS Pathog
. 2021 Dec;
17(12):e1010081.
PMID: 34871323
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice....
4.
Splitt S, Souza S, Valentine K, Castellanos B, Curd A, Hoyer K, et al.
Infect Immun
. 2018 Jul;
86(9).
PMID: 29967089
T cell exhaustion is a state of hyporesponsiveness that develops during many chronic infections and cancer. Neutralization of inhibitory receptors, or "checkpoint blockade," can reverse T cell exhaustion and lead...