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Scott O Sundberg

Explore the profile of Scott O Sundberg including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Myrick J, Pryor R, Palais R, Ison S, Sanford L, Dwight Z, et al.
Clin Chem . 2018 Nov; 65(2):263-271. PMID: 30459167
Background: Extreme PCR in <30 s and high-speed melting of PCR products in <5 s are recent advances in the turnaround time of DNA analysis. Previously, these steps had been...
2.
Pryor R, Myrick J, Palais R, Sundberg S, Paek J, Wittwer C, et al.
Clin Chem . 2017 Aug; 63(10):1624-1632. PMID: 28818830
Background: High-resolution DNA melting analysis of small amplicons is a simple and inexpensive technique for genotyping. Microfluidics allows precise and rapid control of temperature during melting. Methods: Using a microfluidic...
3.
Sundberg S, Wittwer C, Howell R, Huuskonen J, Pryor R, Farrar J, et al.
Clin Chem . 2014 Aug; 60(10):1306-13. PMID: 25117377
Background: Clinical molecular testing typically batches samples to minimize costs or uses multiplex lab-on-a-chip disposables to analyze a few targets. In genetics, multiple variants need to be analyzed, and different...
4.
Sundberg S, Wittwer C, Zhou L, Palais R, Dwight Z, Gale B
Biomed Microdevices . 2014 May; 16(4):639-44. PMID: 24781884
Rare variant enrichment and quantification was achieved by allele-specific, competitive blocker, digital PCR for aiming to provide a noninvasive method for detecting rare DNA variants from circulating cells. The allele-specific...
5.
Sundberg S, Wittwer C, Gao C, Gale B
Anal Chem . 2010 Jan; 82(4):1546-50. PMID: 20085301
An inexpensive plastic disk disposable was designed for digital polymerase chain reaction (PCR) applications with a microfluidic architecture that passively compartmentalizes a sample into 1000 nanoliter-sized wells by centrifugation. Well...
6.
Sundberg S, Wittwer C, Greer J, Pryor R, Elenitoba-Johnson O, Gale B
Biomed Microdevices . 2006 Dec; 9(2):159-66. PMID: 17165128
Solution-phase, DNA melting analysis for heterozygote scanning and single nucleotide polymorphism (SNP) genotyping was performed in 10 nl volumes on a custom microchip. Human genomic DNA was PCR amplified in...