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Scott La

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Articles 7
Citations 53
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Recent Articles
1.
Hight S, Clark T, Kurita K, McMillan E, Bray W, Shaikh A, et al.
Proc Natl Acad Sci U S A . 2022 Nov; 119(49):e2208458119. PMID: 36449542
Determining mechanism of action (MOA) is one of the biggest challenges in natural products discovery. Here, we report a comprehensive platform that uses Similarity Network Fusion (SNF) to improve MOA...
2.
Chang T, Draper J, van den Bout A, Kephart E, Maul-Newby H, Vasquez Y, et al.
PLoS One . 2021 Dec; 16(12):e0261230. PMID: 34919584
The systematic screening of asymptomatic and pre-symptomatic individuals is a powerful tool for controlling community transmission of infectious disease on college campuses. Faced with a paucity of testing in the...
3.
Thornlow B, Hinrichs A, Jain M, Dhillon N, La S, Kapp J, et al.
bioRxiv . 2021 Apr; PMID: 33851162
We report a SARS-CoV-2 lineage that shares N501Y, P681H, and other mutations with known variants of concern, such as B.1.1.7. This lineage, which we refer to as B.1.x (COG-UK sometimes...
4.
Fu P, La S, MacMillan J
J Nat Prod . 2017 Feb; 80(4):1096-1101. PMID: 28225277
Three new cyclohexene amine derivatives, daryamides D-F (1-3), a new arylamine derivative, carpatamide D (4), and a new ornithine lactamization derivative, ornilactam A (5), were isolated from the marine-derived Streptomyces...
5.
Fu P, Legako A, La S, MacMillan J
Chemistry . 2016 Feb; 22(10):3491-3495. PMID: 26834079
Dibohemamines A-C (5-7), three new dimeric bohemamine analogues dimerized through a methylene group, were isolated from a marine-derived Streptomyces spinoverrucosus. The structures determined by spectroscopic analysis were confirmed through the...
6.
Fu P, La S, MacMillan J
J Nat Prod . 2015 Oct; 79(3):455-62. PMID: 26489038
Two new 1,3-oxazin-6-one derivatives (1 and 2) and six new bohemamine-type pyrrolizidine alkaloids (3-8) were isolated from the marine-derived Streptomyces spinoverrucosus strain SNB-048. Their structures including the absolute configurations were...
7.
Fu P, Jamison M, La S, MacMillan J
Org Lett . 2014 Oct; 16(21):5656-9. PMID: 25338006
Inducamides A-C (1-3), three new chlorinated alkaloids featuring an amide skeleton generated by a tryptophan fragment and a 6-methylsalicylic acid unit, were isolated from a chemically induced mutant strain of...