Scott D Gray-Owen
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Explore the profile of Scott D Gray-Owen including associated specialties, affiliations and a list of published articles.
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100
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3258
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Recent Articles
1.
Islam E, Fegan J, Zeppa J, Ahn S, Ng D, Currie E, et al.
Vaccine
. 2025 Jan;
48:126709.
PMID: 39817984
Neisseria gonorrhoeae, which causes the sexually transmitted infection gonorrhea and Neisseria meningitidis, a leading cause of bacterial meningitis and septicemia, are closely related human-restricted pathogens that inhabit distinct primary mucosal...
2.
Fegan J, Islam E, Curran D, Ng D, Au N, Currie E, et al.
NPJ Vaccines
. 2025 Jan;
10(1):10.
PMID: 39814726
Neisseria gonorrhoeae is an on-going public health problem due in part to the lack of success with efforts to develop an efficacious vaccine to prevent this sexually transmitted infection. The...
3.
Mao Y, Jahanshahi S, Malty R, Van Ommen D, Wan Y, Morey T, et al.
Commun Biol
. 2024 Nov;
7(1):1460.
PMID: 39511285
The COVID-19 pandemic has created a global health crisis, with challenges arising from the ongoing evolution of the SARS-CoV-2 virus, the emergence of new strains, and the long-term effects of...
4.
Zeppa J, Fegan J, Maiello P, Islam E, Lee I, Pham C, et al.
bioRxiv
. 2024 Sep;
PMID: 39314429
Retrospective epidemiological studies suggest that the licensed serogroup B meningococcal vaccine 4CMenB (Bexsero) provides some protection against the closely related pathogen Neisseria gonorrhoeae in humans. This result has been replicated...
5.
Islam E, Fegan J, Zeppa J, Ahn S, Ng D, Currie E, et al.
bioRxiv
. 2024 Sep;
PMID: 39314293
Neisseria gonorrhoeae, which causes the sexually transmitted infection gonorrhea and N. meningitidis, a leading cause of bacterial meningitis and septicemia, are closely related human-restricted pathogens that inhabit distinct primary mucosal...
6.
Fegan J, Islam E, Curran D, Ng D, Au N, Currie E, et al.
bioRxiv
. 2024 Sep;
PMID: 39282273
is the causative agent of gonorrhea, an on-going public health problem due in part to the lack of success with efforts to develop an efficacious vaccine to prevent this sexually...
7.
Lee I, Fegan J, Currie E, Bojagora A, Leung N, Rancourt D, et al.
bioRxiv
. 2024 Sep;
PMID: 39282262
is a human-restricted bacteria that is a normal nasopharyngeal resident, yet it can also disseminate, causing invasive meningococcal disease. Meningococci are highly adapted to life in humans, with human-specific virulence...
8.
Lin F, Mabanglo M, Zhou J, Binepal G, Barghash M, Wong K, et al.
J Med Chem
. 2024 Sep;
67(17):15131-15147.
PMID: 39221504
A series of arylsulfones and heteroarylsulfones have previously been demonstrated to dysregulate the conserved bacterial ClpP protease, causing the unspecific degradation of essential cellular housekeeping proteins and ultimately resulting in...
9.
Huang Y, Yoon C, Gandhi A, Hanley T, Castrillon C, Kondo Y, et al.
Commun Med (Lond)
. 2024 Jul;
4(1):128.
PMID: 38956268
Background: Human carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) is an inhibitory cell surface protein that functions through homophilic and heterophilic ligand binding. Its expression on immune cells in human...
10.
Fegan J, Waeckerlin R, Tesfaw L, Islam E, Deresse G, Dufera D, et al.
Front Immunol
. 2024 Jun;
15:1392681.
PMID: 38835751
Background: is a bacterial pathogen that causes a variety of infections across diverse animal species, with one of the most devastating associated diseases being hemorrhagic septicemia. Outbreaks of hemorrhagic septicemia...