Scott Brakenridge
Overview
Explore the profile of Scott Brakenridge including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
414
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0
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Recent Articles
1.
Shankar-Hari M, Francois B, Remy K, Gutierrez C, Pastores S, Daix T, et al.
JCI Insight
. 2025 Feb;
PMID: 39903535
Background: Lymphopenia and failure of lymphocytes to mount an early IFN-γ response correlate with increased mortality in COVID-19. Given the essential role of CD4 helper and CD8 cytotoxic cells in...
2.
Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, et al.
Nat Commun
. 2025 Jan;
16(1):586.
PMID: 39794319
Coronavirus disease 2019 (COVID-19) poses significant risks for solid organ transplant recipients, who have atypical but poorly characterized immune responses to infection. We aim to understand the host immunologic and...
3.
Brakenridge S, Kornblith L, Cuschieri J
J Trauma Acute Care Surg
. 2024 Sep;
PMID: 39225733
Multiple organ failure (MOF) remains a significant challenge for the acute care surgeon, often leading to poor patient outcomes. This comprehensive review explores the etiology, pathophysiology, clinical presentation, diagnosis, management...
4.
Lombardo S, McCrum M, Knudson M, Moore E, Kornblith L, Brakenridge S, et al.
Trauma Surg Acute Care Open
. 2024 Feb;
9(1):e001230.
PMID: 38420604
Introduction: Optimal venous thromboembolism (VTE) enoxaparin prophylaxis dosing remains elusive. Weight-based (WB) dosing safely increases anti-factor Xa levels without the need for routine monitoring but it is unclear if it...
5.
Barrios E, Mazer M, McGonagill P, Bergmann C, Goodman M, Gould R, et al.
medRxiv
. 2023 Sep;
PMID: 37745385
Background: Sepsis remains a major clinical challenge for which successful treatment requires greater precision in identifying patients at increased risk of adverse outcomes requiring different therapeutic approaches. Predicting clinical outcomes...
6.
Daix T, Mathonnet A, Brakenridge S, Dequin P, Mira J, Berbille F, et al.
Ann Intensive Care
. 2023 Mar;
13(1):17.
PMID: 36906875
Background: Profound lymphopenia is an independent predictor of adverse clinical outcomes in sepsis. Interleukin-7 (IL-7) is essential for lymphocyte proliferation and survival. A previous phase II study showed that CYT107,...
7.
Byerly S, Nahmias J, Stein D, Haut E, Smith J, Gelbard R, et al.
Trauma Surg Acute Care Open
. 2022 Jan;
7(1):e000821.
PMID: 35047673
Objectives: Damage control laparotomy (DCL) remains an important tool in the trauma surgeon's armamentarium. Inconsistency in reporting standards have hindered careful scrutiny of DCL outcomes. We sought to develop a...
8.
Knudson M, Moore E, Kornblith L, Shui A, Brakenridge S, Bruns B, et al.
JAMA Surg
. 2021 Dec;
157(2):e216356.
PMID: 34910098
Importance: Pulmonary clots are seen frequently on chest computed tomography performed after trauma, but recent studies suggest that pulmonary thrombosis (PT) and pulmonary embolism (PE) after trauma are independent clinical...
9.
Miranda D, Maine R, Cook M, Brakenridge S, Moldawer L, Arbabi S, et al.
Trauma Surg Acute Care Open
. 2021 Aug;
6(1):e000747.
PMID: 34423134
Objectives: Chronic critical illness (CCI) is a phenotype that occurs frequently in patients with severe injury. Previous work has suggested that inflammatory changes leading to CCI occur early following injury....
10.
Humphry N, Wilson T, Cox M, Carter B, Arkesteijn M, Reeves N, et al.
JMIR Res Protoc
. 2021 Aug;
10(8):e16846.
PMID: 34402798
Background: Older patients account for a significant proportion of patients undergoing colorectal cancer surgery and are vulnerable to a number of preoperative risk factors that are not often present in...