Scott Baskerville
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Explore the profile of Scott Baskerville including associated specialties, affiliations and a list of published articles.
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11
Citations
2679
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Recent Articles
1.
Miller M, Alvizo O, Baskerville S, Chintala A, Chng C, Dassie J, et al.
Faraday Discuss
. 2024 Jun;
252(0):431-449.
PMID: 38832894
Messenger RNA (mRNA) therapies have recently gained tremendous traction with the approval of mRNA vaccines for the prevention of SARS-CoV-2 infection. However, manufacturing challenges have complicated large scale mRNA production,...
2.
Buehler L, Balasubramanian V, Baskerville S, Bailey R, McCarthy K, Rippen M, et al.
Endocr Pract
. 2021 Oct;
28(2):142-147.
PMID: 34600130
Objective: The Alertgy noninvasive continuous glucose monitor (ANICGM) is a novel wristband device that reports glucose levels without entailing skin puncture. This study evaluated the performance of the ANICGM compared...
3.
Wang Y, Baskerville S, Shenoy A, Babiarz J, Baehner L, Blelloch R
Nat Genet
. 2008 Nov;
40(12):1478-83.
PMID: 18978791
Dgcr8 knockout embryonic stem (ES) cells lack microprocessor activity and hence all canonical microRNAs (miRNAs). These cells proliferate slowly and accumulate in G1 phase of the cell cycle. Here, by...
4.
Anderson E, Birmingham A, Baskerville S, Reynolds A, Maksimova E, Leake D, et al.
RNA
. 2008 Mar;
14(5):853-61.
PMID: 18367722
Pairing between the hexamer seed region of a small interfering RNA (siRNA) guide strand (nucleotides 2-7) and complementary sequences in the 3' UTR of mature transcripts has been implicated as...
5.
Vermeulen A, Robertson B, Dalby A, Marshall W, Karpilow J, Leake D, et al.
RNA
. 2007 Apr;
13(5):723-30.
PMID: 17400817
While microRNAs (miRNAs) are recognized as playing a critical role in regulating eukaryotic gene expression, both the mechanism by which these small, noncoding RNAs function and the genes they target...
6.
Rao P, Kumar R, Farkhondeh M, Baskerville S, Lodish H
Proc Natl Acad Sci U S A
. 2006 May;
103(23):8721-6.
PMID: 16731620
Since their discovery as key regulators of early animal development, microRNAs now are recognized as widespread regulators of gene expression. Despite their abundance, little is known regarding the regulation of...
7.
Birmingham A, Anderson E, Reynolds A, Ilsley-Tyree D, Leake D, Fedorov Y, et al.
Nat Methods
. 2006 Feb;
3(3):199-204.
PMID: 16489337
Off-target gene silencing can present a notable challenge in the interpretation of data from large-scale RNA interference (RNAi) screens. We performed a detailed analysis of off-targeted genes identified by expression...
8.
Hornstein E, Mansfield J, Yekta S, Hu J, Harfe B, McManus M, et al.
Nature
. 2005 Dec;
438(7068):671-4.
PMID: 16319892
MicroRNAs (miRNAs) are an abundant class of gene regulatory molecules (reviewed in refs 1, 2). Although computational work indicates that miRNAs repress more than a third of human genes, their...
9.
Giraldez A, Cinalli R, Glasner M, Enright A, Thomson J, Baskerville S, et al.
Science
. 2005 Mar;
308(5723):833-8.
PMID: 15774722
MicroRNAs (miRNAs) are small RNAs that regulate gene expression posttranscriptionally. To block all miRNA formation in zebrafish, we generated maternal-zygotic dicer (MZdicer) mutants that disrupt the Dicer ribonuclease III and...
10.
Baskerville S, Bartel D
RNA
. 2005 Feb;
11(3):241-7.
PMID: 15701730
MicroRNAs (miRNAs) are short endogenous RNAs known to post-transcriptionally repress gene expression in animals and plants. A microarray profiling survey revealed the expression patterns of 175 human miRNAs across 24...