Scott A Soleimanpour
Overview
Explore the profile of Scott A Soleimanpour including associated specialties, affiliations and a list of published articles.
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49
Citations
4939
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Recent Articles
1.
Kadowaki A, Wheeler M, Li Z, Andersen B, Lee H, Illouz T, et al.
Nat Neurosci
. 2025 Mar;
28(3):470-486.
PMID: 40033124
Astrocytes promote neuroinflammation and neurodegeneration in multiple sclerosis (MS) through cell-intrinsic activities and their ability to recruit and activate other cell types. In a genome-wide CRISPR-based forward genetic screen investigating...
2.
Levi-DAncona E, Walker E, Zhu J, Deng Y, Sidarala V, Stendahl A, et al.
bioRxiv
. 2025 Feb;
PMID: 39974969
Activation of innate immune signaling occurs during the progression of immunometabolic diseases, including type 2 diabetes (T2D), yet the impact of innate immune signaling on glucose homeostasis is controversial. Here,...
3.
Walker E, Pearson G, Lawlor N, Stendahl A, Lietzke A, Sidarala V, et al.
Science
. 2025 Feb;
:eadf2034.
PMID: 39913641
Mitochondrial damage is a hallmark of metabolic diseases, including diabetes, yet the consequences of compromised mitochondria in metabolic tissues are often unclear. Here, we report that dysfunctional mitochondrial quality control...
4.
Wang H, Kazaleh M, Gioscia-Ryan R, Millar J, Temprano-Sagrera G, Wood S, et al.
bioRxiv
. 2024 Nov;
PMID: 39554010
Abdominal aortic aneurysms (AAAs) are a degenerative aortic disease and associated with hallmarks of aging, such as mitophagy. Despite this, the exact associations among mitophagy, aging, and AAA progression remain...
5.
Xu X, Bell T, Le T, Zhao I, Walker E, Wang Y, et al.
Diabetes
. 2024 Sep;
73(12):2034-2044.
PMID: 39325584
Article Highlights:
6.
Lietzke A, Bealer E, Crumley K, King J, Stendahl A, Zhu J, et al.
bioRxiv
. 2024 Aug;
PMID: 39211191
Pluripotent stem cell (SC)-derived islets offer hope as a renewable source for β cell replacement for type 1 diabetes (T1D), yet functional and metabolic immaturity may limit their long-term therapeutic...
7.
Rohli K, Stubbe N, Walker E, Pearson G, Soleimanpour S, Stephens S
JCI Insight
. 2024 Jun;
9(15).
PMID: 38935435
ER stress and proinsulin misfolding are heralded as contributing factors to β cell dysfunction in type 2 diabetes, yet how ER function becomes compromised is not well understood. Recent data...
8.
Robertson C, Elgamal R, Henry-Kanarek B, Arvan P, Chen S, Dhawan S, et al.
Mol Metab
. 2024 Jun;
86:101973.
PMID: 38914291
Background: Type 1 diabetes (T1D) is a complex multi-system disease which arises from both environmental and genetic factors, resulting in the destruction of insulin-producing pancreatic beta cells. Over the past...
9.
Li J, Zhu J, Deng Y, Reck E, Walker E, Sidarala V, et al.
bioRxiv
. 2024 Jun;
PMID: 38895283
Proteotoxicity is a contributor to the development of type 2 diabetes (T2D), but it is unknown whether protein misfolding in T2D is generalized or has special features. Here, we report...
10.
Venkatasubramanian S, Plumlee C, Dill-McFarland K, Cohen S, Gern B, Rane D, et al.
Nat Microbiol
. 2024 Mar;
9(4):949-963.
PMID: 38528148
A polymorphism causing deficiencies in Toll-interacting protein (TOLLIP), an inhibitory adaptor protein affecting endosomal trafficking, is associated with increased tuberculosis (TB) risk. It is, however, unclear how TOLLIP affects TB...