Scott A Heldt
Overview
Explore the profile of Scott A Heldt including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
28
Citations
804
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Liu Y, McAfee S, Guley N, Del Mar N, Bu W, Heldt S, et al.
eNeuro
. 2017 Aug;
4(4).
PMID: 28828401
Mild traumatic brain injury (mTBI) can cause severe long-term cognitive and emotional deficits, including impaired memory, depression, and persevering fear, but the neuropathological basis of these deficits is uncertain. As...
2.
Gao Y, Heldt S
Front Cell Neurosci
. 2016 Mar;
10:39.
PMID: 26973458
Although it is generally recognized that certain α-subunits of γ-aminobutyric acid type A receptors (GABAARs) form enriched clusters on the axonal initial segment (AIS), the degree to which these clusters...
3.
Engin E, Smith K, Gao Y, Nagy D, Foster R, Tsvetkov E, et al.
Elife
. 2016 Mar;
5:e14120.
PMID: 26971710
Recent findings indicate a high level of specialization at the level of microcircuits and cell populations within brain structures with regards to the control of fear and anxiety. The hippocampus,...
4.
Cook M, Baker J, Heldt S, Williams R, Hamre K, Lu L
Physiol Genomics
. 2015 May;
47(8):308-17.
PMID: 25991709
Alcoholism, stress, and anxiety are strongly interacting heritable, polygenetic traits. In a previous study, we identified a quantitative trait locus (QTL) on murine chromosome (Chr) 1 between 23.0 and 31.5...
5.
Gao Y, Heldt S
Behav Neurosci
. 2015 Jan;
129(1):50-61.
PMID: 25621792
Nitric oxide (NO) is an important molecule for the proper development and function of the central nervous system. In this study, we investigated the behavioral alterations in the neuronal NO...
6.
Reiner A, Heldt S, Presley C, Guley N, Elberger A, Deng Y, et al.
Int J Mol Sci
. 2015 Jan;
16(1):758-87.
PMID: 25561230
We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice subjected to 50-60 psi...
7.
Fitzgerald A, Wright B, Heldt S
Psychopharmacology (Berl)
. 2014 Feb;
231(9):1865-96.
PMID: 24563183
Rationale: Zolpidem is a positive allosteric modulator of γ-aminobutyric acid (GABA) with preferential binding affinity and efficacy for α1-subunit containing GABA(A) receptors (α1-GABA(A)Rs). Over the last three decades, a variety...
8.
Wright B, Gluszek C, Heldt S
Psychopharmacology (Berl)
. 2014 Feb;
231(15):2967-79.
PMID: 24531568
Rationale: Zolpidem is a short-acting, non-benzodiazepine hypnotic that acts as a full agonist at α1-containing GABAA receptors. Overall, zolpidem purportedly has fewer instances of abuse and dependence than traditionally used...
9.
Chen Y, Wang B, Liu D, Li J, Xue Y, Sakata K, et al.
J Neurosci
. 2014 Feb;
34(7):2464-70.
PMID: 24523537
The excessive accumulation of soluble amyloid peptides (Aβ) plays a crucial role in the pathogenesis of Alzheimer's disease (AD), particularly in synaptic dysfunction. The role of the two major chaperone...
10.
Heldt S, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler K
J Neurosci
. 2014 Feb;
34(7):2444-50.
PMID: 24523535
Brain-derived neurotrophic factor (BDNF) is known to have an integral role in establishing stable memories after learning events. The neuroplasticity induced by Pavlovian fear conditioning has likewise been shown to...