Saurabh D Patel
Overview
Explore the profile of Saurabh D Patel including associated specialties, affiliations and a list of published articles.
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15
Citations
692
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Recent Articles
1.
Ba A, Thiam L, Pouye M, Guo Y, Patel S, Sene S, et al.
medRxiv
. 2024 Nov;
PMID: 39484257
The cysteine-rich protective antigen (PfCyRPA) is a promising target as a next-generation blood-stage malaria vaccine and together with PCRCR complex members, the reticulocyte binding-like homologous protein 5 (PfRh5) and the...
2.
Thiam L, McHugh K, Ba A, Li R, Guo Y, Pouye M, et al.
NPJ Vaccines
. 2024 Oct;
9(1):198.
PMID: 39448626
Vaccines to the Plasmodium falciparum reticulocyte binding-like protein homologue 5 (PfRH5) target the blood-stage of the parasite life cycle. PfRH5 has the potential to trigger the production of strain-transcendent antibodies...
3.
Mangou K, Moore A, Thiam L, Ba A, Orfano A, Desamours I, et al.
Sci Rep
. 2022 Nov;
12(1):19403.
PMID: 36371450
The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an efficacious vaccine is the...
4.
Sheng Z, Bimela J, Katsamba P, Patel S, Guo Y, Zhao H, et al.
Front Immunol
. 2022 Jan;
12:811632.
PMID: 35046963
Accumulation of somatic hypermutation (SHM) is the primary mechanism to enhance the binding affinity of antibodies to antigens . However, the structural basis of the effects of many SHMs remains...
5.
Shakya B, Patel S, Tani Y, Egan E
Elife
. 2021 May;
10.
PMID: 34028351
Invasion of human erythrocytes by the malaria parasite is a multi-step process. Previously, a forward genetic screen for host factors identified erythrocyte CD55 as essential for invasion, but its specific...
6.
Cosmanescu F, Katsamba P, Sergeeva A, Ahlsen G, Patel S, Brewer J, et al.
Neuron
. 2018 Nov;
100(6):1385-1400.e6.
PMID: 30467080
Binding between DIP and Dpr neuronal recognition proteins has been proposed to regulate synaptic connections between lamina and medulla neurons in the Drosophila visual system. Each lamina neuron was previously...
7.
Dankwa S, Lim C, Bei A, Jiang R, Abshire J, Patel S, et al.
Nat Commun
. 2016 Apr;
7:11187.
PMID: 27041489
Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are...
8.
Bei A, Patel S, Volkman S, Ahouidi A, Ndiaye D, Mboup S, et al.
PLoS One
. 2014 Mar;
9(3):e90928.
PMID: 24603696
A challenge to conducting high-impact and reproducible studies of the mechanisms of P. falciparum drug resistance, invasion, virulence, and immunity is the lack of robust and sustainable in vitro culture...
9.
Patel S, Ahouidi A, Bei A, Dieye T, Mboup S, Harrison S, et al.
J Infect Dis
. 2013 Aug;
208(10):1679-87.
PMID: 23904294
Plasmodium falciparum is an intracellular protozoan parasite that infects erythrocytes and hepatocytes. The blood stage of its life cycle causes substantial morbidity and mortality associated with millions of infections each...
10.
Badiane A, Bei A, Ahouidi A, Patel S, Salinas N, Ndiaye D, et al.
Clin Vaccine Immunol
. 2013 Jun;
20(8):1238-45.
PMID: 23761656
Plasmodium falciparum utilizes multiple ligand-receptor interactions for invasion. The invasion ligand EBA-175 is being developed as a major blood-stage vaccine candidate. EBA-175 mediates parasite invasion of host erythrocytes in a...