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Satoshi Onodera

Explore the profile of Satoshi Onodera including associated specialties, affiliations and a list of published articles. Areas
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Articles 167
Citations 2298
Followers 0
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Recent Articles
1.
Liu W, Wang F, Li C, Otkur W, Hayashi T, Mizuno K, et al.
J Photochem Photobiol B . 2021 Feb; 216:112147. PMID: 33561689
Ultraviolet B (UVB) from the sunlight is a major environmental cause for human skin damages, inducing cell death, inflammation, senescence and even carcinogenesis. The natural flavonoid silibinin, clinically used as...
2.
Liu W, Ji Y, Sun Y, Si L, Fu J, Hayashi T, et al.
Arch Biochem Biophys . 2020 Jun; 689:108458. PMID: 32524997
Our previous studies showed that silibinin promoted activation of caspases to induce apoptosis in human breast cancer MCF-7 cells by down-regulating the protein expression level of estrogen receptor (ER) α...
3.
Si L, Fu J, Liu W, Hayashi T, Mizuno K, Hattori S, et al.
Arch Biochem Biophys . 2020 Feb; 685:108284. PMID: 32014401
We reported previously that higher doses (150-250 μM) of silibinin enhanced fission and inhibited fusion of mitochondria, accompanying apoptosis of double-positive breast cancer cell line MCF-7 cells and triple-negative breast...
4.
Li J, Wang J, Liu W, Hayashi T, Itoh K, Onodera S, et al.
Free Radic Res . 2020 Jan; 54(1):64-75. PMID: 31905044
Bleomycin is a glycopeptide antibiotic that is widely employed in the therapy of a range of lymphomas and germ cell tumours. But the therapeutic efficacy of bleomycin is limited by...
5.
Liu P, Cui L, Liu B, Liu W, Hayashi T, Mizuno K, et al.
Physiol Behav . 2019 Nov; 213:112689. PMID: 31669775
Alzheimer's disease (AD) is a neurodegenerative disease, mainly characterized by cognitive dysfunction and memory impairment. Due to its pathological similarities to type 2 diabetes mellitus (T2DM), such as β-amyloid deposition,...
6.
Si L, Fu J, Liu W, Hayashi T, Nie Y, Mizuno K, et al.
Mol Cell Biochem . 2019 Oct; 463(1-2):189-201. PMID: 31612353
Human triple negative breast cancer cells, MDA-MB-231, show typical epithelial to mesenchymal transition associated with cancer progression. Mitochondria play a major role in cancer progression, including metastasis. Changes in mitochondrial...
7.
Zhang X, Chen Y, Zhao Y, Liu W, Hayashi T, Mizuno K, et al.
Int Immunopharmacol . 2019 Aug; 76:105845. PMID: 31470266
Background: Extracellular matrix (ECM) comprising the environments of multicellular society has a dynamic network structure. Collagen is one of the ubiquitous components of ECM. Collagen affects the inflammatory response by...
8.
Liu X, Long X, Gao Y, Liu W, Hayashi T, Mizuno K, et al.
J Cell Physiol . 2019 Aug; 235(2):1821-1837. PMID: 31432516
Extracellular matrix (ECM) has a marked influence on adipose tissue development. Adipose tissue formation is initiated with proliferation of preadipocytes and migration before undergoing further differentiation into mature adipocytes. Previous...
9.
Sun Y, Yang J, Liu W, Yao G, Xu F, Hayashi T, et al.
Mol Cell Biochem . 2019 Jun; 460(1-2):81-92. PMID: 31183735
High levels of circulating free fatty acids often trigger pancreatic β cell dysfunction during the development of type 2 diabetes. Silibinin, the main component of Silybum marianum fruit extract (silymarin),...
10.
Liu B, Liu W, Liu P, Liu X, Song X, Hayashi T, et al.
Neurochem Res . 2019 May; 44(8):1818-1829. PMID: 31102026
Excessive physical exercise (overtraining; OT) increases oxidative stress and induces damage in multiple organs including the brain, especially the hippocampus that plays an important role in learning and memory. Silibinin,...