Sathivel Ponniah
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Explore the profile of Sathivel Ponniah including associated specialties, affiliations and a list of published articles.
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10
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619
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Recent Articles
1.
Li G, Wang J, Liao P, Bartels P, Zhang H, Yu D, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(21):E4288-E4295.
PMID: 28490495
Alternative splicing changes the Ca1.2 calcium channel electrophysiological property, but the in vivo significance of such altered channel function is lacking. Structure-function studies of heterologously expressed Ca1.2 channels could not...
2.
Ye H, Tan Y, Ponniah S, Takeda Y, Wang S, Schachner M, et al.
EMBO J
. 2007 Nov;
27(1):188-200.
PMID: 18046458
Apical dendrites of pyramidal neurons in the neocortex have a stereotypic orientation that is important for neuronal function. Neural recognition molecule Close Homolog of L1 (CHL1) has been shown to...
3.
Hossain Z, Mohamed Ali S, Ko H, Xu J, Peng Ng C, Guo K, et al.
Proc Natl Acad Sci U S A
. 2007 Jan;
104(5):1631-6.
PMID: 17251353
Wwtr1 is a widely expressed 14-3-3-binding protein that regulates the activity of several transcription factors involved in development and disease. To elucidate the physiological role of Wwtr1, we generated Wwtr1-/-...
4.
Tan E, Hooi S, Laban M, Wong E, Ponniah S, Wee A, et al.
Cancer Res
. 2005 Nov;
65(22):10330-7.
PMID: 16288022
The CCAAT/enhancer binding protein alpha (C/EBPalpha) is vital for establishing normal hepatic energy homeostasis and moderating hepatocellular growth. CEBPA loss-of-function mutations identified in acute myeloid leukemia patients support a tumor...
5.
Huang G, Lu H, Hao A, Ng D, Ponniah S, Guo K, et al.
Mol Cell Biol
. 2004 Sep;
24(19):8447-56.
PMID: 15367666
Mitochondria play essential roles in cellular energy production via the oxidative phosphorylation system (OXPHOS) consisting of five multiprotein complexes and also in the initiation of apoptosis. NADH:ubiquinone oxidoreductase (complex I)...
6.
Le H, Ponniah S, Pallen C
Biochem Biophys Res Commun
. 2004 Jan;
314(2):321-9.
PMID: 14733908
Studies in cultured cells have implicated protein tyrosine phosphatase alpha (PTPalpha) as a potential regulator of insulin signaling. The physiological role of PTPalpha in insulin action was investigated using gene-targeted...
7.
Skelton M, Ponniah S, Wang D, Doetschman T, Vorhees C, Pallen C
Brain Res
. 2003 Aug;
984(1-2):1-10.
PMID: 12932834
Receptor PTPalpha is a widely expressed transmembrane enzyme enriched in brain. PTPalpha knockout (PTPalpha(-/-)) mice are viable and display no gross abnormalities. Brain and embryo derived fibroblast src and fyn...
8.
Zhou Z, Toh S, Chen Z, Guo K, Peng Ng C, Ponniah S, et al.
Nat Genet
. 2003 Aug;
35(1):49-56.
PMID: 12910269
The thermogenic activity of brown adipose tissue (BAT), important for adaptive thermogenesis and energy expenditure, is mediated by the mitochondrial uncoupling protein1 (Ucp1) that uncouples ATP generation and dissipates the...
9.
Zeng L, Si X, Yu W, Le H, Ng K, Teng R, et al.
J Cell Biol
. 2003 Jan;
160(1):137-46.
PMID: 12515828
We investigated the molecular and cellular actions of receptor protein tyrosine phosphatase (PTP) alpha in integrin signaling using immortalized fibroblasts derived from wild-type and PTP alpha-deficient mouse embryos. Defects in...
10.
Brenner S, Venkatesh B, Yap W, Chou C, Tay A, Ponniah S, et al.
Proc Natl Acad Sci U S A
. 2002 Feb;
99(5):2936-41.
PMID: 11867707
The lck gene encodes a lymphocyte-specific protein-tyrosine kinase that is implicated in T cell maturation and signaling. In mammals, the transcription of the lck gene is regulated by two independent...