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» Authors » Sascha Verbruggen

Sascha Verbruggen

Explore the profile of Sascha Verbruggen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 27
Citations 405
Followers 0
Related Specialties
Critical Care
General Medicine
Pediatrics
Top 10 Co-Authors
Koen Joosten
Greet Van den Berghe
Ilse Vanhorebeek
Pieter J Wouters
Gonzalo Garcia Guerra
Lyvonne N Tume
Lies Langouche
Sarah Vander Perre
Dieter Mesotten
Lynne Latten
Published In
Crit Care
Pediatr Crit Care Med
JPEN J Parenter Enteral Nutr
N Engl J Med
Clin Nutr
Affiliations
Soon will be listed here.
Recent Articles
1.
Alterations in the lipid profile of critically ill children in relation to outcome
De Bruyn L, Vander Perre S, Verbruggen S, Joosten K, Van den Berghe G, Langouche L
Crit Care . 2025 Mar; 29(1):99. PMID: 40038820
Background: Critically ill adults typically develop hypocholesterolemia, associated with poor outcome. Whether similar alterations occur in critically ill children is less clear. Methods: In secondary analyses of the PEPaNIC RCT...
2.
PN Administration in Critically Ill Children in Different Phases of the Stress Response
Joosten K, Verbruggen S
Nutrients . 2022 May; 14(9). PMID: 35565787
Nutritional support is an important part of the treatment of critical ill children and the phase of disease has to be taken into account. The metabolic stress response during acute...
3.
Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial
Vanhorebeek I, Jacobs A, Mebis L, Dulfer K, Eveleens R, Van Cleemput H, et al.
Crit Care . 2022 May; 26(1):133. PMID: 35549984
Background: Many critically ill children face long-term developmental impairments. The PEPaNIC trial attributed part of the problems at the level of neurocognitive and emotional/behavioral development to early use of parenteral...
4.
Quality improvement intervention to stimulate early mobilisation of critically ill children
Zanen-van den Adel T, Dijk M, de Heer M, Hoekstra S, Steenhorst J, van Rosmalen J, et al.
Nurs Crit Care . 2022 Feb; 28(4):545-553. PMID: 35191161
Background: Immobility during hospital stay is associated with muscle weakness, delirium, and delayed neurocognitive recovery. Early mobilisation of critically ill adults improves their physical functioning and shortens the duration of...
5.
Role of extracorporeal membrane oxygenation in pediatric cancer patients: a systematic review and meta-analysis of observational studies
Slooff V, Hoogendoorn R, Nielsen J, Pappachan J, Amigoni A, Caramelli F, et al.
Ann Intensive Care . 2022 Jan; 12(1):8. PMID: 35092500
Background: The use of extracorporeal membrane oxygenation (ECMO) in pediatric patients with underlying malignancies remains controversial. However, in an era in which the survival rates for children with malignancies have...
6.
Association of monocyte HLA-DR expression over time with secondary infection in critically ill children: a prospective observational study
Hagedoorn N, Kolukirik P, Nagtzaam N, Nieboer D, Verbruggen S, Joosten K, et al.
Eur J Pediatr . 2021 Nov; 181(3):1133-1142. PMID: 34755207
An impaired immune response could play a role in the acquisition of secondary infections in critically ill children. Human leukocyte antigen-DR expression on monocytes (mHLA-DR) has been proposed as marker...
7.
Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?
Vanhorebeek I, Malarvannan G, Guiza F, Poma G, Derese I, Wouters P, et al.
Environ Int . 2021 Nov; 158:106962. PMID: 34739923
Background: Children who have been critically ill face long-term developmental impairments. Iatrogenic exposure to di(2-ethylhexyl)phthalate (DEHP), a plasticizer leaching from plastic indwelling medical devices used in the pediatric intensive care...
8.
Practical strategies to implement the ESPNIC Nutrition Clinical recommendations into PICU practice
Tume L, Ista E, Verbruggen S, Chaparro C, Moullet C, Latten L, et al.
Clin Nutr ESPEN . 2021 Mar; 42:410-414. PMID: 33745616
Background: The European Society of Pediatric and Neonatal Intensive Care (ESPNIC) published 32 clinical recommendations around supporting nutrition in critically ill children following an extensive review of the literature online...
9.
Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections' Collaborative of the European Society of Pediatric and Neonatal Intensive Care
Rimensberger P, Kneyber M, Deep A, Bansal M, Hoskote A, Javouhey E, et al.
Pediatr Crit Care Med . 2020 Oct; 22(1):56-67. PMID: 33003177
Objectives: In children, coronavirus disease 2019 is usually mild but can develop severe hypoxemic failure or a severe multisystem inflammatory syndrome, the latter considered to be a postinfectious syndrome, with...
10.
Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit
De Bruyn A, Gunst J, Goossens C, Vander Perre S, Guerra G, Verbruggen S, et al.
Crit Care . 2020 Sep; 24(1):536. PMID: 32867803
Background: In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical ventilation, and shortened PICU stay. We hypothesized that fasting-induced ketogenesis...