Sascha Gross-Hardt
Overview
Explore the profile of Sascha Gross-Hardt including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
59
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Recent Articles
1.
Blum C, Gross-Hardt S, Steinseifer U, Neidlin M
Cardiovasc Eng Technol
. 2022 Jan;
13(4):638-649.
PMID: 35031981
Purpose: Thrombosis ranks among the major complications in blood-carrying medical devices and a better understanding to influence the design related contribution to thrombosis is desirable. Over the past years many...
2.
Grunwald A, Korte J, Wilmanns N, Winkler C, Linden K, Herberg U, et al.
Cardiovasc Eng Technol
. 2021 Dec;
13(3):495-503.
PMID: 34850371
Purpose: Patients with a functionally univentricular heart represent one of the most common severe cardiac lesions with a prevalence of 3 per 10,000 live births. Hemodynamics of the singular ventricle...
3.
Hugenroth K, Borchardt R, Ritter P, Gross-Hardt S, Meyns B, Verbelen T, et al.
Sci Rep
. 2021 Aug;
11(1):16800.
PMID: 34408243
Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report...
4.
Hildebrand S, Gross-Hardt S, Schmitz-Rode T, Steinseifer U, Jansen S
J Artif Organs
. 2021 May;
25(1):1-8.
PMID: 33956261
An in-vitro study was conducted to investigate the general feasibility of using only one pumping chamber of the SynCardia total artificial heart (TAH) as a replacement of the single ventricle...
5.
Winkler C, Neidlin M, Sonntag S, Grunwald A, Gross-Hardt S, Breuer J, et al.
Comput Biol Med
. 2020 Aug;
123:103908.
PMID: 32768048
Left ventricular stroke work is an important prognostic marker to analyze cardiac function. Standard values for children are, however, missing. For clinicians, standards can help to improve the treatment decision...
6.
Kaesler A, Rosen M, Schlanstein P, Wagner G, Gross-Hardt S, Schmitz-Rode T, et al.
ASAIO J
. 2019 Dec;
66(6):683-690.
PMID: 31789656
Wearable extracorporeal membrane oxygenation (ECMO) circuits may soon become a viable alternative to conventional ECMO treatment. Common device-induced complications, however, such as blood trauma and oxygenator thrombosis, must first be...
7.
Gross-Hardt S, Hesselmann F, Arens J, Steinseifer U, Vercaemst L, Windisch W, et al.
Crit Care
. 2019 Nov;
23(1):348.
PMID: 31694688
Background: Extracorporeal carbon dioxide removal (ECCOR) uses an extracorporeal circuit to directly remove carbon dioxide from the blood either in lieu of mechanical ventilation or in combination with it. While...
8.
Wu P, Gross-Hardt S, Boehning F, Hsu P
Biomech Model Mechanobiol
. 2019 Oct;
19(2):591-602.
PMID: 31612342
Hemolysis is a major concern in blood-circulating devices, which arises due to non-physiological stresses on red blood cells from ambient flow environment or moving mechanical structures. Computational fluid dynamics (CFD)...
9.
Gross-Hardt S, Boehning F, Steinseifer U, Schmitz-Rode T, Kaufmann T
J Biomech Eng
. 2018 Nov;
141(2).
PMID: 30458464
The reduction of excessive, nonphysiologic shear stresses leading to blood trauma can be the key to overcome many of the associated complications in blood recirculating devices. In that regard, computational...
10.
Wu P, Boehning F, Gross-Hardt S, Hsu P
Artif Organs
. 2018 Oct;
42(10):E290-E303.
PMID: 30375677
Hemolysis is one of the most challenging issues faced by blood contacting devices. Empirical hemolysis models often relate hemolysis to shear stress and exposure time. These models were generally derived...