Sascha Baumann
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Explore the profile of Sascha Baumann including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
335
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Recent Articles
1.
Falckenhayn C, Bienkowska A, Sohle J, Wegner K, Raddatz G, Kristof B, et al.
Front Aging
. 2024 Mar;
4:1258184.
PMID: 38500495
Changes in DNA methylation patterning have been reported to be a key hallmark of aged human skin. The altered DNA methylation patterns are correlated with deregulated gene expression and impaired...
2.
Wenz F, Schmidt I, Leichner A, Lichti T, Baumann S, Andrae H, et al.
Adv Mater
. 2021 Aug;
33(37):e2008617.
PMID: 34338367
Shape morphing implicates that a specific condition leads to a morphing reaction. The material thus transforms from one shape to another in a predefined manner. In this paper, not only...
3.
Elgaher W, Hamed M, Baumann S, Herrmann J, Siebenburger L, Krull J, et al.
Chemistry
. 2020 Jan;
26(32):7219-7225.
PMID: 31984562
Lack of new antibiotics and increasing antimicrobial resistance are among the main concerns of healthcare communities nowadays, and these concerns necessitate the search for novel antibacterial agents. Recently, we discovered...
4.
Panter F, Krug D, Baumann S, Muller R
Chem Sci
. 2018 Jun;
9(21):4898-4908.
PMID: 29910943
There is astounding discrepancy between the genome-inscribed production capacity and the set of known secondary metabolite classes from many microorganisms as detected under laboratory cultivation conditions. Genome-mining techniques are meant...
5.
Wang Y, Schnell B, Baumann S, Muller R, Begley T
J Am Chem Soc
. 2017 Jan;
139(5):1742-1745.
PMID: 28040895
The biosynthesis of branched alkoxy groups, such as the unique t-butyl group found in a variety of natural products, is still poorly understood. Recently, cystobactamids were isolated and identified from...
6.
Herrmann J, Lukezic T, Kling A, Baumann S, Huttel S, Petkovic H, et al.
Curr Top Microbiol Immunol
. 2016 Oct;
398:339-363.
PMID: 27738913
Natural products continue to be a predominant source for new anti-infective agents. Research at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the Helmholtz Centre for Infection Research (HZI)...
7.
Baumann S, Herrmann J, Raju R, Steinmetz H, Mohr K, Huttel S, et al.
Angew Chem Int Ed Engl
. 2014 Dec;
53(52):14605-9.
PMID: 25510965
The development of new antibiotics faces a severe crisis inter alia owing to a lack of innovative chemical scaffolds with activities against Gram-negative and multiresistant pathogens. Herein, we report highly...
8.
Wolf A, Schoof S, Baumann S, Arndt H, Kirschner K
J Comput Aided Mol Des
. 2014 Oct;
28(12):1205-15.
PMID: 25281020
The bacterial ribosome is a major target of naturally occurring thiopeptides antibiotics. Studying thiopeptide (e.g. thiostrepton) binding to the GAR's 23S·L11 ribosomal subunit using docking methods is challenging. Regarding the...
9.
Etzbach L, Plaza A, Garcia R, Baumann S, Muller R
Org Lett
. 2014 Apr;
16(9):2414-7.
PMID: 24735013
Cystomanamides A-D were isolated as novel natural product scaffolds from Cystobacter fuscus MCy9118, and their structures were established by spectroscopic techniques including 2D NMR, LC-SPE-NMR/-MS, and HR-MS. The cystomanamides contain...
10.
Lichtenecker R, Ellinger B, Han H, Jadhav K, Baumann S, Makarewicz O, et al.
Chembiochem
. 2013 Oct;
14(18):2492-9.
PMID: 24151156
Growing resistance to antibiotics, as well as newly emerging pathogens, stimulate the investigation of antimicrobial peptides (AMPs) as therapeutic agents. Here, we report a new library design concept based on...