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Sarah Leary

Explore the profile of Sarah Leary including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 2442
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Recent Articles
1.
Shatara M, Schieffer K, Melas M, Varga E, Thomas D, Bucknor B, et al.
Front Oncol . 2024 Sep; 14:1453309. PMID: 39309743
Introduction: In the setting of pediatric and adolescent young adult cancer, increased access to genomic profiling has enhanced the detection of genetic variation associated with cancer predisposition, including germline syndromic...
2.
Hall E, Perez F, Cole B, Paulson V, Leary S, Ronsley R
J Pediatr Hematol Oncol . 2024 Aug; 46(7):e541-e543. PMID: 39196641
Encephalocraniocutaneous lipomatosis (ECCL) is a rare genetic condition with well-described skin, ocular, and central nervous system findings. Several case reports have been documented demonstrating the presence of low-grade gliomas in...
3.
Familiar A, Kazerooni A, Anderson H, Lubneuski A, Viswanathan K, Breslow R, et al.
ArXiv . 2023 Dec; PMID: 38106459
Pediatric brain and spinal cancers remain the leading cause of cancer-related death in children. Advancements in clinical decision-support in pediatric neuro-oncology utilizing the wealth of radiology imaging data collected through...
4.
Boop S, Bonda D, Randle S, Leary S, Vitanza N, Crotty E, et al.
Pediatr Neurosurg . 2023 May; 58(3):150-159. PMID: 37232001
Introduction: Subependymal giant cell astrocytoma (SEGA) is the most common CNS tumor in patients with tuberous sclerosis complex (TSC). Although these are benign, their proximity to the foramen of Monroe...
5.
Cooney T, Lindsay H, Leary S, Wechsler-Reya R
Neoplasia . 2022 Dec; 35:100861. PMID: 36516489
Medulloblastoma (MB) is the most common malignant central nervous system tumor of childhood, comprising a heterogenous group of tumors each with distinct biology, clinical behavior, and prognosis. Long-term survival remains...
6.
Lilly J, Rokita J, Mason J, Patton T, Stefankiewiz S, Higgins D, et al.
Neoplasia . 2022 Nov; 35:100846. PMID: 36335802
Pediatric brain tumors are the leading cause of cancer-related death in children in the United States and contribute a disproportionate number of potential years of life lost compared to adult...
7.
Hansford J, Huang J, Endersby R, Dodgshun A, Li B, Hwang E, et al.
Neurooncol Adv . 2022 Jun; 4(1):vdac056. PMID: 35664557
Background: Pineoblastoma is a rare brain tumor usually diagnosed in children. Given its rarity, no pineoblastoma-specific trials have been conducted. Studies have included pineoblastoma accruing for other embryonal tumors over...
8.
Lazow M, Nievelstein M, Lane A, Bandopadhayhay P, DeWire-Schottmiller M, Fouladi M, et al.
Neuro Oncol . 2022 Feb; 24(9):1598-1608. PMID: 35148393
Background: Cross-sectional tumor measures are traditional clinical trial endpoints; however volumetric measures may better assess tumor growth. We determined the correlation and compared the prognostic impact of cross-sectional and volumetric...
9.
Bartels U, Onar-Thomas A, Patel S, Shaw D, Fangusaro J, Dhall G, et al.
Neuro Oncol . 2021 Dec; 24(6):974-983. PMID: 34850169
Background: The study aimed to evaluate whether simplified chemotherapy followed by dose-reduced irradiation was effective for treating patients (ages 3-21 years) with localized germinoma. The primary endpoint was 3-year progression-free...
10.
Chen J, Leary S, Barnhouse V, Sarkaria J, Harley B
Tissue Eng Part A . 2021 Aug; 28(7-8):330-340. PMID: 34435883
Glioblastoma (GBM) displays diffusive invasion throughout the brain microenvironment, which is partially responsible for its short median survival rate (<15 months). Stem-like subpopulations (GBM stem-like cells, GSCs) are believed to...