Sarah A Gebb
Overview
Explore the profile of Sarah A Gebb including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
546
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Recent Articles
1.
Ferretti A, Fortwendel J, Gebb S, Barrington R
J Immunol
. 2016 Jun;
197(2):470-9.
PMID: 27279372
Pulmonary alveolar proteinosis (PAP) is a rare lung syndrome caused by the accumulation of surfactants in the alveoli. The most prevalent clinical form of PAP is autoimmune PAP (aPAP) whereby...
2.
Chettimada S, Gupte R, Rawat D, Gebb S, McMurtry I, Gupte S
Am J Physiol Lung Cell Mol Physiol
. 2014 Dec;
308(3):L287-300.
PMID: 25480333
Severe pulmonary hypertension is a debilitating disease with an alarmingly low 5-yr life expectancy. Hypoxia, one of the causes of pulmonary hypertension, elicits constriction and remodeling of the pulmonary arteries....
3.
Chettimada S, Joshi S, Alzoubi A, Gebb S, McMurtry I, Gupte R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2014 Jul;
307(7):L545-56.
PMID: 25063801
Although hypoxia is detrimental to most cell types, it aids survival of progenitor cells and is associated with diseases like cancer and pulmonary hypertension in humans. Therefore, understanding the underlying...
4.
Gebb S, DeCoux A, Waggoner A, Wilson G, Gillespie M
Neonatology
. 2012 Nov;
103(2):91-7.
PMID: 23154780
Background: Numerous studies in cultured cells indicate that damage to mitochondrial DNA (mtDNA) dictates cellular responses to oxidant stress, yet the consequences of mtDNA damage have not been studied directly...
5.
Gairhe S, Bauer N, Gebb S, McMurtry I
Am J Physiol Lung Cell Mol Physiol
. 2012 Aug;
303(9):L767-77.
PMID: 22923644
Myoendothelial gap junctional signaling mediates pulmonary arterial endothelial cell (PAEC)-induced activation of latent TGF-β and differentiation of cocultured pulmonary arterial smooth muscle cells (PASMCs), but the nature of the signal...
6.
Gairhe S, Bauer N, Gebb S, McMurtry I
Am J Physiol Lung Cell Mol Physiol
. 2011 Aug;
301(4):L527-35.
PMID: 21803868
Myoendothelial gap junctions are involved in regulating systemic arterial smooth muscle cell phenotype and function, but their role in the regulation of pulmonary arterial smooth muscle cell (PASMC) phenotype is...
7.
Homma N, Nagaoka T, Morio Y, Ota H, Gebb S, Karoor V, et al.
J Cardiovasc Pharmacol
. 2007 Dec;
50(6):697-702.
PMID: 18091588
We have previously reported that vasoconstrictor sensitivity to KCl (a receptor-independent and voltage-gated Ca influx-mediated vasoconstrictor) is augmented in the chronically hypoxic hypertensive rat pulmonary circulation probably through increased Rho...
8.
Oka M, Karoor V, Homma N, Nagaoka T, Sakao E, Golembeski S, et al.
Cardiovasc Res
. 2007 Mar;
74(3):377-87.
PMID: 17346686
Objective: It has been reported that dehydroepiandrosterone is a pulmonary vasodilator and inhibits chronic hypoxia-induced pulmonary hypertension. Additionally, dehydroepiandrosterone has been shown to improve systemic vascular endothelial function. Thus, we...
9.
Kaufman J, Sakao E, Oka M, Nagaoka T, Oliver-Picket C, Jones P, et al.
Chest
. 2005 Dec;
128(6 Suppl):610S.
PMID: 16373862
No abstract available.
10.
Nagaoka T, Gebb S, Karoor V, Homma N, Morris K, McMurtry I, et al.
J Appl Physiol (1985)
. 2005 Dec;
100(3):996-1002.
PMID: 16322374
The fawn-hooded rat (FHR) develops severe pulmonary hypertension (PH) when raised for the first 3-4 wk of life in the mild hypoxia of Denver's altitude (5,280 ft.). The PH is...